Final Program

09.00-17.00 CocADDICT Meeting (closed)
Organizer: Veronique Deroche-Gamonet (FR) and Rainer Spanagel (DE)
Room H2037

13.00-17.00 Pre-Conference Workshop on 
Effective Preparation of Power Point Presentations and Manuscripts for Publication

Organizer: Michie Hesselbrock, Victor Hesselbrock and Margaret Murray (US)
pre-registration required! click here to register
Room H1028

TimeTopicsPresenters
13:00 – 13:15IntroductionSusumu Higuchi, MD, PhD
Michie Hesselbrock, PhD
13:15 – 13:45Preparing Power Point Presentations Marc Shuckit, MD
13:45 – 14:15Peer review process, editor’s role and authors’ responsibilitiesVictor Hesselbrock, PhD
14:15 – 14:45Responding to the reviewers commentsMargaret Murray, PhD
14:45 – 15:00Common problems encountered by new and non-English speaking investigatorsMichie Hesselbrock, PhD
15:00 – 15:15 Break
15:15 – 15:30 Advice from editors:
* things that make good submissions
* things editors wish authors wouldn’t do
Each editor will share his/her thoughts
Rainer Spanagel, MD,
Victor Hesselbrock, PhD
Michie Hesselbrock, PhD
Susumu Higuchi, MD, PhD
Margaret Murray, PhD
15:30 – 17:00 Round Table Discussions, mentoring, Q and A All participants
TIMEPRECLINICAL CNSCLINICAL CNSGENETICS & EPIGENETICSALCOHOL-INDUCED ORGAN
DAMAGE
8.00
Opening of Registration
9.00 -9.15
OPENING OF THE WORLD CONGRESS

Susumu Higuchi (JA) ISBRA President
Tomáš Zima (CZ) ESBRA President
Rainer Spanagel (DE) Congress President
9.15-10.00
1st PLENARY LECTURE

George Koob (Director NIAAA, US): Historical aspects and research highlights of the last 50 years
of alcohol research

Chair: Rainer Spanagel (DE)
10.00-10.30
Coffee Break
10.30-12.00Can We Learn From Other Addictions? A DSM-Based Animal Model: Behavior, Networks, Physiology and Translation

Chair: Veronique Deroche-Gamonet (FR)
Co-Chair: Dai Stephens (UK)

Veronique Deroche-Gamonet (FR)
A DSM based model on cocaine addiction

Nazzareno Cannella (DE)
Divergent Brain Adaptations in Addicted-Like and Non-Addicted-Like Rats after Prolonged Cocaine Self-Administration: A Multimodal Neuroimaging Study.

Cyril Herry (FR)
Physiological correlates of cocaine addiction

Marco Leyton (CA)
What has neuroimaging told us about addictions?

Discussant: Dai Stephens (UK)
New Findings Linking Impulsivity, Reward, and Alcohol Sensitivity

Chair: Jessica Weafer (US)
Co-Chair: Robert Leeman (US)

Christian Hendershot (CA)
Investigating impulsivity-related traits as moderators of acute alcohol responses and laboratory self-administration in late adolescence

Robert Leeman: (US)
Explaining Impulsivity and Subjective Response to Alcohol Use: Multiple Methodological Approaches

Jessica Weafer (US)
Brain activation during response inhibition predicts sensitivity to drug and non-drug reward

Theodora Duka (UK)
The role of inhibitory control and reward sensitivity in impulse behaviours; relevance for alcohol use

Discussant: Reinout Wiers (NL)
The Role of Genetics in Elucidating the Causes of Alcohol Dependence

Chair: Marcella Rietschel (DE)
Co-Chair: Laura Bierut (US)

Nicholas G. Martin (AU)
How twin studies can inform us about the etiology of addiction

Laura Bierut (US)
Systematic Genome-wide Approaches of Alcohol Dependence

Brien Riley (US)
Cross-species Convergence in the Genetics of Ethanol Response and Dependence

Felix Stickel (CH)
Alcohol-induced Somatic Disorders

Discussant: John Crabbe (US)
11th International Symposium on ALPD and Cirrhosis
“Emerging Therapeutic Targets”


Organizers:
Helmut Karl Seitz (DE)
Samir Zakhari (US)
Bin Gao (US)
Hidekazu Tsukamoto (US)

Opening Remarks by Helmut Karl Seitz (DE) Inflammation and Immunology of ALPD

Moderated by Helmut Karl Seitz (DE) and Craig McClain (US)

Steven Dooley (DE)
Effects of alcohol on TGF-ß mediated hepatocyte apoptosis

Emanuel Albano (IT)
Oxidant stress and adaptive immunity in ASH and NASH

Hana Algül (DE)
Autophagy and chronic inflammation in the pancreas

Henrik Thorlacius (SE)
Neutrophil extracellular traps trigger trypsin activation, pathological inflammation and tissue damage in severe acute pancreatitis
12.00 - 12.45
2nd PLENARY LECTURE

Wolfgang Sommer (DE): Lost in Translation

Chair: Wim van den Brink (NL)
13.15-14.15
Publish or Perish - a Lunch Debate


Chair: Rainer Spanagel (DE)
Co-Chair: Henry Kranzler (US)

Rainer Spanagel (DE)
Addiction Biology – an Editor´s Perspective on Publishing

Henry Kranzler (US)
Predatory Publishers and Other Challenges in Academic Publishing

Anton Bespalov (RU)
Good Scientific practise in preclinical and translational research
12.45-14.30
ISBRA Membership Boardmeeting
(closed)
12.45-14.30
Lunch and Poster session
14.30-16.00Recent Advances from Preclinical Models of Compulsive and Relapsing Alcohol-Seeking

Chair: Andrew Lawrence (AU)
Co-Chair: Ainhoa Bilbao (DE)

Andrew Holmes (US)
Neural circuits regulating punished alcohol-seeking

Valentina Vengeliene (DE)
The alcohol deprivation effect model for studying relapse behaviour

Joyce Besheer (US)
Relapse-like drinking following stress hormone exposure

Andrew Lawrence (AU)
Stress-induced relapse to alcohol seeking – involvement of ascending peptide systems

Discussant: Ainhoa Bilbao (DE)
How Behavioural Paradigms of Implicit Learning Can Help Understanding Development and Maintenance of Alcoholism

Chair: Ulrich Zimmermann (DE)
Co-Chair: Valerie Voon (UK)

Ulrich Zimmermann (DE)
Impulsivity enhances the impact of context cues during Pavlovian-to-Instrumental-Transfer

Maria Garbusow (DE)
Neurobiological correlates of Pavlovian-to-Instrumental-Transfer in alcohol relapse

Michael Smolka (DE) Good goals, bad habits: Will they help us to better understand vulnerability for alcoholism?

Valerie Voon (UK) Waiting impulsivity in humans: relevance to implicit learning
Epigenetic Studies in Alcohol Consumption and Addiction

Chair: Dayne Mayfield (US)
Co-Chair: Subhash Pandey (US)

Claes Wahlestedt (US)
Crosstalk between epigenetic and inflammatory signaling pathways in alcohol dependence

Georgy Bakalkin (SE)
DNA methylation signature of alcoholism: analysis of human brain

Subhash Pandey (US)
Histone methylation mechanisms in the comorbidity of anxiety and alcoholism

Ke Xu (US)
Methylome-wide association for alcohol consumption in a community population

Christine-Johanna Macare (UK) EWAS of psychosocial stress in participants of the IMAGEN cohort.

Discussant: Sean P. Farris (US)
11th International Symposium on ALPD and Cirrhosis

Novel Targets of ALPD


Moderated by Samir Zakhari (US) and Kazuhiko Koike (JP)

Vikas Dudeja (US)
HSP70 as a therapeutic target of pancreatic cancer

Craig McClain (US)
Malnutrition and Alcoholic Liver Disease

Bernd Schnabl (US)
Targeting intestinal dysbiosis in alcoholic liver disease

Jonas Rosendahl (DE)
Genetics of alcoholic chronic pancreatitis
16.00-16.30
Coffee Break
16.30-18.00Drosophila Melanogaster as a Genetic Model Organism for Alcoholism Research

Chair: Laura Velo Escarcena (DE)
Co-Chair: Fred Wolf (US)

Fred Wolf (US)
Gene transcription by acute inebriation leads to presynaptic changes and behavioural plasticity

Karla Kaun (US)
Neural and molecular mechanisms underlying alcohol reward prediction

Henrike Scholz (DE)
Hangover links nuclear RNA signalling to cAMP regulation via phosphodiesterase 4d orthologe dunce

Nigel Atkinson (US)
Pinning down the gene regulatory networks that generate alcohol tolerance

Discussant: Henrike Scholz (DE)
Taking Control Over Drinking: Translational Approaches to Address Compulsive Alcohol Intake

Chair: Rajita Sinha (US)
Co-Chair: Pia Steensland (SE)

Pia Steensland (SE)
Novel dopamine agents to reduce impulsivity and drinking behavior in animal models of alcohol use disorder

Vijay Ramchandani (US)
Using human laboratory models of alcohol self-administration to examine relationships between cognitive control and alcohol use

Nitya Jayaram-Lindstrom (SE)
Working memory training in alcohol dependence: a randomised clinical trial

Ismene Petrakis (US)
New clinical targets for alcohol use disorders: evaluation using a laboratory paradigm

Discussant: Falk Kiefer (DE)
Pharmacogenetic Studies in Alcohol Use Disorders – Clinical Findings and Treatment Implications

Chair: Raymond Anton (US)
Co-Chair: Marcella Rietschel (DE)

Raymond Anton (US)
Does OPRM1 asp40 Allele Status Influence Naltrexone Response? Results From a Prospective Randomized Clinical Trial

Henry Kranzler (US)
Personalizing Topiramate Treatment for AUD: Clinical Applications and Future Developments

Victor Karpyak (US)
Search For Predictors of Acamprosate Response: Clinical and Genetic Markers Associated With Length of Sobriety

Franziska Degenhardt (DE)
Involvement of GATA4 in Alcohol Dependence, Relapse Risk and Acamprosate Treatment Response

Discussant: Paul Haber (AT)
11th International Symposium on ALPD and Cirrhosis

Selected Oral Presentation by Travel Awardees


Moderated by Garry Murray (US) and Yoshiyuki Takei (JP)

Liana Asatryan (US)
P2X7 receptor antagonism inhibits inflammatory response in brain induced by exposure to combined ethanol and high-fat diet

Keane Lai (US)
Stearoyl-CoA desaturase in alcoholic liver fibrosis and cancer

Armen Petrosyan (US)
The mechanism of alcohol-induced Golgi fragmentation in hepatocytes

Carlos Sanz-Garcia (US)
Differential role for the transcriptional and non-transcriptional functions of IRF-3 in chronic ethanol-induced liver injury

Ali Dehnad (US)
Hepatic stellate cells regulate CCR2 mRNA stability and recruitment of inflammatory cells via NOX4 in alcoholic liver injury


Moderated by Gary Murray (NIAAA) and Yoshiyuki Takei (Mie Univ., Japan)
 5 selected abstracts (10+5 min each)
18.00-19.00
DA Pharma Symposium & Snacks

Sodium Oxybate:
A Promising Treatment Option for Alcohol-Dependent Patients with a Very High Drinking Risk Level


David Nutt (UK): Target population for pharmacotherapies
Antonio Gual (ES) Sodium oxybate: efficacy results of a placebo-controlled European trial
Bo Söderpalm (SE) Safety of sodium oxybate: a meta-analysis of data from clinical trials, retrospective surveys and pharmacovigilance

Presentations will be followed by a panel discussion chaired by David Nutt (UK)

Snacks
TIMEPRECLINICAL CNSTREATMENT:TRANSLATIONAL
AND CLINICAL ASPECTS
GENETICS & EPIGENETICSALCOHOL-INDUCED ORGAN DAMAGE
8.15 -9.00
3rd PLENARY LECTURE

Antonello Bonci
(Scientific Director NIDA, US): Molecular Theories of Addiction

Chair: Veronique Deroche-Gamonet (FR)
9.00-10.30Alcohol Actions: From Atoms to Systems Molecules

Chair: Joydip Das (US)
Co-Chair: R. Adron Harris (US)

James R Trudell (US)
Electrostatic interactions in ligand-gated ion channels that affect alcohol action

Rebecca J. Howard (US)
Selective spirits: Physicochemical determinants for alcohol modulation of ligand-gated ion channels

Joydip Das (US)
Presynaptic Munc13-1 binds ethanol and affects ethanol sedation sensitivity

Enrico Sanna (IT)
Ethanol modulation of HCN-mediated currents (Ih) in rat hippocampal CA3 pyramidal neurons: Involvement of the AC/cAMP/PKA pathway and influence on neuronal excitability

Discussant: R. Adron Harris (US)
Deep Brain Stimulation - Is It Still a Perspective for Treatment of Severe Alcohol Addiction?

Chair: Christine Winter (DE)
Co-Chair: Andrea Kühn (DE)

Ulf Müller (DE)
DBS in alcohol addiction – Where do we stand? A clinical overview

Ravit Hadar (DE)
Anything to learn from rats?

Michael Nitsche (DE)
tDCS - an alternative?

Hagai Bergman (IL)
Advancements and advantages of adaptive DBS.

Discussant: Andrea Kühn (DE)
Epigenetic Studies in Alcohol Consumption and Addiction Part II

Chair: Dorit Ron (US)
Co-Chair: Kent E. Hutchison (US)

Markus Heilig (SE)
Epigenetic reprogramming of the mPFC transcriptome in alcohol dependence

Dorit Ron (US)
Novel Molecular Mediators of Alcohol-Dependent Structural Plasticity And Alcohol Consumption

Igor Ponomarev (US)
Mechanistic insights into epigenetic modulation of ethanol consumption

Kent E. Hutchison (US)
Epigenetic regulation of pro-inflammatory genes and changes in brain structure and function

Discussant: Antonio Noronha
11th International Symposium on ALPD and Cirrhosis

Liver-Brain Inflammatory Axis in ALPD


Moderated by Hidekazu Tsukamoto (US) and Laura Nagy (US)

Yedy Israel (CL)
THE LIVER-BRAIN AXIS: Brain acetaldehyde and alcohol addiction

Tatiana Kisseleva (US)
IL-17 and alcoholic liver and brain inflammation

Fulton Crews (US)
Mechanisms of alcohol-induced brain innate immune gene induction

Christoph Buettner (US)
Hypothalamic dysfunction as a key mechanism for alcoholic liver disease

12.20
The 12th ALPD Symposium Announcement and
Closing Remarks


Kazuhiko Koike (JP), Hidekazu Tsukamoto (US)
10.30-11.00
Coffee Break
11.00-12.30Alcohol Actions via Neuronal Ensembles

Chair: Bruce Hope (US)
Co-Chair: Eisuke Koya (UK)

Bruce T. Hope (US)
Neuronal ensembles in addiction

Simone Pfarr (DE)
Cues associated with alcohol seeking activate neuronal ensembles in the infralimbic cortex that mediate alcohol seeking in rats

Eisuke Koya (UK)
Enhanced excitability of nucleus accumbens, but not orbitofrontal cortex neuronal ensembles following sucrose memory recall: reversal by extinction.

Olivier George (US)
Pharmacogenetic and optogenetic control of alcohol dependence through inactivation of a withdrawal neuronal ensemble in the central amygdala.

Discussant: John Woodward (US)
From Medication Development to Market Introduction

Chair: Barbara J. Mason (US)
Co-Chair: Boris Tabakoff (US)

Barbara J. Mason (US)
A Human Lab Model as a Screen of Novel Drugs for Theraputic Potential for Alcoholism

Boris Tabakoff (US)
The Road to Recovery: Perspective from a Small Biotech Firm

Conor Farren (IE)
Advances in Treatment of AUD: Technology and Pharmacotherapy

Christoph von der Goltz (DK)
Nalmefene in the Treatment of Alcohol Dependence in Europe from Regulatory Approval to Clinical Use

Discussant: George Koob (US)
Development of Novel Clinical Phenotypes for Genetic Analyses in Alcohol Use Disorders

Chair: Michie Hesselbrock (US)
Co-Chair: Ulrich Preuss (DE)

Victor Hesselbrock (US)
Novel clinical phenotypes of alcohol dependence

Marc Schuckit (US)
The low level of response to alcohol: relationships to other risk markers, possible brain mechanisms, specific genes and environmental mediators

Sachio Matsushita (JP)
Perceived response to alcohol as a phenotype for risk of alcohol related problems in young Japanese adults

Ulrich Preuss (DE)
DSM5 criteria as phenotypes for genetic association studies

Discussant: Laura Almacy (US)
Cross-Talk Between Stress Responses and the Innate Immunity in ASH/NASH/

Chair: Kenichi Ikejima (JP)
Co-Chair: Gavin E. Arteel (US)

Jun Xu (US)
NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation

Kai Markus Schneider (DE)
Securing Microbial Cross-border Control: Gut liver crosstalk at the interface of health and disease

Shunhei Yamashina (JP)
The impairment of autophagic function is involved in the progression of alcoholic and non-alcoholic liver diseases.

Gavin E. Arteel (US)
Transitional changes in the hepatic ECM in response to stress and injury

Discussant: John J Lemasters (US)
12.45 - 14.15HOT TOPIC Lunch Symposium: GPCR Heteromers in Addiction

Chair: Kjell Fuxe (SE)
Co-Chair: Anita C Hansson (DE)

Kjell Fuxe (SE)
GPCR heteroreceptor as an emerging target for treatment of mental disorders

Dominique Massotte (FR)
Co-localization of mu and delta opioid receptors in the nervous system using double fluorescent knock-in mice

Dasiel O. Borroto Escuela (SE)
The role of homo and heteroreceptor complexes in voluntary alcohol intake and cocaine use disorder

Laura Broccoli (IT)
Interaction of the corticotropin hormone receptor subtype 1 with the dopaminergic system in alcohol dependence

Discussant: Anita C Hansson (DE)
I. Young Investigator Lunch Symposium

Chair: Peter Dodd (AU)
Co-Chair: Felix Stickel (CH)

Leon G. Coleman Jr (US)
Neurotoxicity to ethanol via MIR LET 7 and HMGB1 in microvesicles

Olli Kärkkäinen (FI)
Exposure to ethanol induces metabolic and bioenergetics changes in induced pluripotent stem cell-derived astrocytes

Alexander Glahn (DE)
The role of natriuretic peptides in alcohol dependent patients: the epigenetic regulation of GATA4-dependent brain natriuretic peptide (BNP) expression in alcohol dependent patients during detoxification treatment

Lucia Marti-Prats (ES)
Intra-pVTA ethanol induces conditioned place preference that is reinstated by salsolinol: role of mu opioid receptors

Sean P. Farris (US)
Neuroimmune gene expression involved in alcohol use disorders

Esi Domi (SE)
The PPARγ receptor agonist pioglitazone protects against neuronal and cognitive damage elicited by binge alcohol exposure in the rat

Discussant: ISBRA Education Committee
Alcohol & Alcoholism
Editorial Board
Meeting


(closed)

13.00- 14.00

Addiction Biology
Editorial Board
Meeting


(closed)

13.00-14.00
12.30 - 14.15

Lunch and Poster session
14.15-15.45Alcohol Actions on the Corticolimbic System

Chair: Jeff Weiner (US)
Co-Chair: Louise Adermark (SE)

Sven Kroener (US)
Effect of Acamprosate on Cognitive Flexibility and Glutamatergic Transmission in the Medial Prefrontal Cortex in Two Rodent Models of Alcohol Drinking

John Woodward (US)
Actions of Acute and Chronic Ethanol on Orbitofrontal Cortex Neurons

Neil Harrison (US)
Alcohol Binge Drinking and Resting Membrane Potential: Arrested Development?

Jeff Weiner (US)
Mesolimbic Adaptations that May Contribute to the Comorbidity Between Anxiety Disorders and Alcoholism

Discussant: Louise Adermark (SE)
Gut-Brain Axis and Alcohol Use Disorder: a Translational Prospective

Chair: Elisabet Jerlhag (SE)
Co-Chair: Lorenzo Leggio (US)

Andrey E. Ryabinin (US)
Ghrelin signaling regulates alcohol intake in rodents

Yanina Pepino (US)
Bypassing sweets for alcohol: alcohol pharmacokinetics and alcohol effects in bariatric patients

Petra Suchankova Karlsson (SE)
Associations between GLP-1 receptor and ghrelin gene polymorphisms and alcohol use disorder in humans

Lorenzo Leggio (US)
Ghrelin as a potential new target for alcoholism treatment: recent clinical data

Discussant: Elisabet Jerlhag (SE)
WHO-ISBRA Joint Symposium: Alcohol and Drug Diagnoses in the International Classification of Diseases

Chair: John Saunders (AU)
Co-Chair: Karl Mann (DE)

John Saunders (AU) and Sawitri Assanangkornchai (TH)
Alcohol and drug use disorder diagnoses in ICD-11 and DSM-5: Commonality and Differences

Hans-Jurgen Rumpf (DE)
Epidemiological findings relevant to the development of ICD 11

Jonathan Chick (UK)
The contribution of diagnostic systems to precision in treatment research.

Vladimir Poznyak (CH)
An update on ICD-11 taxonomy of disorders due to psychoactive substance use and related health conditions

Discussant: Susumu Higuchi (JP)
NIAAA-ESBRA Joint Symposium: Mechanism for Alcohol-Induced Organ Damage

Chair: Helmut Karl Seitz (DE)
Co-Chair: Gary Murray (US)

Rajanikanth Vadigepalli (US)
Integrative biology approaches to unterstanding alcohol liver disease

Patricia E. Molina (US)
Physiological mechanism underlying alcohol-induced tissue injury

Sebastian Mueller (DE)
Alcohol and iron: a complex relationship

Claus Hellerbrand (DE)
Obesity - a lubricant for the development and progression of alcoholic liver disease

Discussant: Helena Cortez-Pinto (PT)
15.45-16.30
4th PLENARY LECTURE - Isaacson Award Lecture

Karl Mann
(Professor Emeritus at Heidelberg University): Progress in treatment research:
which way to the promised land?

Chair: Boris Tabakoff (US)

16.30-16.45
Coffee Break
16.45-18.15Alcohol Actions on Brain Reward, Stress & Cognition Systems

Chair: Nicholas W. Gilpin (US)
Co-Chair: Ingrid Nylander (SE)

Lawrence J. Chandler (US)
Role of the infralimbic cortex in response strategy selection and habitual ethanol consumption  

Ingrid Nylander (SE)
Adolescent alcohol exposure – effects on endogenous opioid peptides and in vivo dopamine dynamics

Nicholas W. Gilpin (US)
Intra-cerebral and intra-nasal melanocortin-4 receptor antagonist blocks withdrawal hyperalgesia in alcohol-dependent rats

Thomas Louis Kash (US)
Chronic alcohol induced changes in extended amygdala neuronal function in mice and monkeys
The Clinical Effects of High-Dose Baclofen in the Treatment of Alcohol Dependence: Results from Four Randomized Clinical Trials

Chair: Reinout Wiers (NL)
Co-Chair: Wim van den Brink (NL)

Christian Müller (DE)
Results from the German Baclad Clinical Trial and additional neuroimaging results

Philippe Jaury (FR)
High dose baclofen for the treatment of alcohol drinkers (bacloville)

Esther Beraha (NL)
Efficacy and safety of high-dose baclofen for the treatment of alcohol dependence: a multicentre, randomised, double-blind controlled trial

Michel Reynaud (FR)
A randomized, double blind, placebo-controlled efficacy study of high-dose baclofen in alcohol dependent patients: the ‘ALPADIR’ study

Discussant: Kyriaki Nikolaou (UK)
WHO-ISBRA Joint Symposium: Are Behavioural Addictions True Addictions? Discussion of Controversies and Their Relevance to ICD-11 Development

Chair: Susumu Higuchi (JP)
Co-Chair: Vladimir Poznyak (WHO) (CH)

Short introduction by:
Vladimir Poznyak (CH)
Behavioural addictions in the context of ICD-11 development

Marc Potenza (US)
Do neurobiological findings support the view that behavioural addictions are addictions?

Henrietta Bowden-Jones (UK)
Pathological gambling in ICD 11: ddictioan or impulse control disorder?

Susumu Higuchi (JP)
Internet use disorder or gaming disorder - consideration for inclusion in ICD-11

Joël Billieux (BE)
Diagnosing behavioral addictions: Risks associated with atheoretical and confirmatory conceptualizations

Discussant: John Saunders (US)
Alcoholic and Non-Alcoholic Liver Disease: Differences and Similarities

Chair: Manuela Neuman (CA)
Co-Chair: Sebastian Mueller (DE)

Stephen Malnick (IL)
Microbiome and alcoholic liver disease

Manuela Neuman (CA)
Alcoholic and non-alcoholic liver disease, similarities and differences

Carol Casey (US)
Ethanol administration reduces lipophagy coincident with a marked reduction in the function and activity of Rab7

Paula Hoffman (US)
Genomics, cell signaling and the  immune system in alcohol drinking: the brain-liver connection?

Discussant: Sebastian Mueller (DE)
18.15-19.00
5th PLENARY LECTURE

Rajita Sinha
(US): Can Glucocorticoid Adaptations Explain Compulsive Alcohol Motivation and Relapse?

Chair: Falk Kiefer (DE)
19.30-...
ISBRA Board Meeting - Location will be announced
TIMEPRECLINICAL CNSNEUROIMAGINGFASDALCOHOL-INDUCED ORGAN DAMAGE
8.15 - 9.00
6th PLENARY LECTURE

Brigitte Kieffer
(CA): Opioids and reward

Chair: Markus Heilig (SE)
9.00 - 10.30Actions of Opioid Antagonists: Behaviour, Circuitry and Genetics

Chair: Petri Hyytiä (FI)
Co-Chair: Annika Thorselll(SE)

Petri Hyytiä (FI)
The role of nucleus accumbens connections in alcohol and naltrexone actions revealed by manganese-enhanced MRI

Santiago Canals (ES)
Longitudinal study of functional and microstructural alterations in brain networks during alcohol intoxication, abstinence, and naltrexone treatment

Annika Thorsell (SE) and Rick Bernardi (DE)
The OPRM1 A118G SNP in alcohol and nicotine reinforcement and treatment response to naltrexone: Evidence from a humanized mouse model & A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology

Chiara Giuliano (UK)
Alcohol-seeking behavior is attenuated by inhibiting µ-opioid receptors

Discussant: Esa Korpi (FI)
Addiction as an Aberrant Network State in the Brain

Chair: Wolfgang Sommer (DE)
Co-Chair: Rita Goldstein (US)

Rita Goldstein (US)
Cognitive functioning as a marker of resting-state connectivity in cocaine addiction

Angelo Bifone (IT)
Modular (re)organization of functional connectivity in alcohol dependence

Martin F. Gerchen (DE)
Neurofeedback as an interventional tool for alcohol addiction – the systems biology of addiction (SyBil-AA) fMRI neurofeedback study

Markus Heilig (SE)
Electromagnetic stimulation in the study and treatment of addiction: From animal models to human applications

Discussant: Markus Heilig (SE)
FASD: Basic Research Targeted to the Current Challenges

Chair: Kenneth R. Warren (US)
Co-Chair: Consuelo Guerri (ES)

Karen Moritz (AU)
Prenatal alcohol exposure and developmental programming of adult disease

Consuelo Guerri (ES)
ROLE OF THE TLR4 IMMUNE response in ethanol-induced neurodevelopmental alterations IN FETAL ALCOHOL SPECTRUM DISORDERS

Sergey M. Zimatkin (BY)
Maternal alcohol consumption in rats induces an irreversible disturbances in offspring brain cortex

Jennifer Thomas (US)
Choline supplementation as a treatment for FASD: Effects on phospholipids

Discussant: Kenneth R. Warren (US)
Brain Meets Liver: Looking at Things from Both Sides Now

Chair: Sebastian Mueller (DE)
Co-Chair: Marc Schuckit (US)

Marc Schuckit (US)
Genetic risk factors for heavy drinking and for specific consequences

Magali Sasso (FR)
CAP- a novel way to measure fatty liver

Sebastian Mueller (DE)
Liver monitoring in addicted patients: Update 2016

Ioan Sporea (RO)
Which are the shear wave elastography methods for the evaluation of liver fibrosis?

Discussant: Laurent Sandrin (FR)

10.30 -11.00
Coffee Break
11.00 - 12.30

Manipulations on Memory Reconsolidation as a Novel Strategy to Prevent Relapse in Addiction

Chair: Segev Barak (IL)
Co-Chair: Valentina Vengeliene (DE)

Rita Fuchs (US)
Basolateral Amygdala – Dorsal Hippocampus Interaction in Instrumental Cocaine Memory Reconsolidation

Segev Barak (IL)
Prevention of relapse to drug and alcohol seeking by memory replacement in rodent models: from behavior to molecules.

Michael Saladin (US)
Administration of propranolol following trauma memory reactivation attenuates trauma but not alcohol related cue reactivity in individuals with PTSD and comorbid alcohol dependence

Ravi Das (UK)
Pharmacological and behavioral reconsolidation manipulations for targeting maladaptive drug memories in humans

Discussant: Dorit Ron (US)
ICCAM Experimental Platform: Assessing Brain Mechanisms Involved in Relapse and Impact of Pharmacological Modulation

Chair: vAnne Lingford-Hughes (UK)
Co-Chair: Wim van den Brink (NL)

Anne Lingford-Hughes (UK)
Overview of ICCAM: principles, assessments and imaging paradigms

Rebecca Elliott (UK)
Impact of DRD3 antagonism on brain mechanisms in addiction

Liam Nestor (UK)
The effects of opioid blockade with naltrexone on fronto-striatal domains of addictive behaviour in alcohol addiction

Remy Flechais (UK)
The effects of NK1 antagonism on responses to negative emotionally salient cues in addiction

Discussant: Wim van den Brink (NL)
Early Identification of Gestational Alcohol Exposure and Fetal Alcohol Spectrum Disorders in the CIFASD Cohort

Chair: Michael E. Charness (US)
Co-Chair: Christina D. Chambers (US)

Rajesh Miranda (US)
miRNA Biomarkers for Fetal Alcohol Exposure in Pregnant Women

Dipak Sarkar (US)
Identification of Alcohol-Induced Epigenetic Marks in Maternal-Child Pairs

Julie Kable (US)
The Use of Cardiac Orienting Responses as an Early Biomarker of Alcohol-Related Neurodevelopmental Impairment

Kirsten A. Donald (ZA)
Imaging The Neonatal Brain In Prenatal Alcohol Exposure: Multimodal MRI Findings

Discussant: Christina D. Chamber (US)
LASBRA-ESBRA Joint Symposium: The Role of Acetaldehyde in the Action of Ethanol

Chair: Yedi Israel (CL)
Co-Chair: Mikko Salaspuro (FI)

Alessandra Tiziana Peana (IT)
Role of ethanol-derived acetaldehyde and acetaldehyde after oral adsorption in the motiviational properties of ethanol

Maria Elena Quintanilla (CL)
Reinforcement by acetaldehyde-dopamine products leading to early ethanol intake shift to glutamate-related mechanisms to perpeatuate intake. A new therapeutic option

Eduardo Karahanian (CL)
Acetaldehyde and fenofibrate: a new old drug that markedly inhibits ethanol consumption

Mikko Salaspuro (FI)
Major role of acetaldehyde in upper GI tract cancer

Discussant: Carlos Manuel Gonzales Aragón (ES)
12.30-14.15
Lunch and Poster Session
12.30-14.15Short Lunch Symposium: The Use of Post-Mortem Human Brain Tissue in Alcohol Research

Chair: Anita Hansson (DE)
Co-Chair: Georgy Bakalkin (SE)

Jillian Kril (AU)
The pros and cons of the use of post-mortem human brain tissue in alcohol research – Experiences from the NSW Brain Resource Centre

Anita Hansson (DE)
Convergent studies on neurotransmitter adaptations in alcohol dependent rats and human alcoholics

Olli Kärkkäinen (FI)
Twenty years of expression studies on post-mortem brain of Cloninger Type I and II alcoholics

Discussant: Dayne Mayfield (US)
II. Young Investigator Lunch Symposium Part 2

Chair: Toshikazu Saito (JP)
Co-Chair: Tomohiro Shirasaka (JP)

Tomohiro Shirasaka (JP)
Epidemiology and Clinical Characteristics of Social isolation (Hikikomori) and Internet Addiction in Japan

Woraphat Ratta-apha (TH)
Amphetamine use during pregnancy and its related problems at Siriraj Hospital

Chia-chun Hung (ID)
Neurocognitive study on Ketamine abusers in Taiwan

Masaya Tayama (JP)
The study of effectiveness of antidepressant and acamprosate to the depressive patients with alcohol use disorders

Discussant: Toshikazu Saito
ESBRA BOARD
MEETING


(closed)

11.00-16.00
HOT TOPIC Lunch Symposium: The Steatosis in Alcoholic Liver Disease - Cross Talk in the Liver

Chair: Akiko Eguchi  (US)
Co-Chair: Yoshiyuki Takei  (JP)
 
Kenichi Ikejima (JP)
Innate immune regulation in the pathogenesis of steatohepatitis

Borna Relja (DE)
Impact of acute, sub-acute and chronic alcohol consumption on the danger response after experimental and clinical trauma

Esteban Gabazza (JP)
Protein S exacerbates alcoholic hepatitis by prolonging survival and promoting activation of liver natural killer T cells

Akiko Eguchi  (US)
Pathogenesis mediated by extracellular vesicles in alcoholic steatohepatitis

Discussant: Yoshiyuki Takei (JP)
14.15-15.45Ethanol and Glycine Receptors – Involvement in Pharmacodynamic Effects of Ethanol and Potential Targets for Treatment of Alcohol Use Disorders.

Chair: Bo Söderpalm (SE)
Co-Chair: Luis Aguayo (CL)

Luis Aguayo (CL)
Alpha1 GlyRs are important for ethanol-induced sedation. Implications for drug development.


Adron Harris (US)
Glycine receptor transmembrane regions and alcohol action: linking atoms to behavior.

Jiang-Hong Ye (US)
Extrasynaptic glycine receptors of rat lateral habenula neurons: a therapeutic target for ethanol-intake and withdrawal-induced pain

Helga Höifödt-Lidö (SE)
Development of glycinergic therapeutics for alcohol use disorders

Discussant: Bo Söderpalm (SE)
Multimodal Neuroimaging in Alcoholism: Recent Advances for Relapse Prediction

Chair: Jenny Ceccarini (BE)
Co-Chair: Andreas Heinz (DE)

Sabine Vollstädt-Klein (DE)
Effects of cue-exposure-treatment and single-dose nalmefene on neural cue-reactivity in alcohol-dependent patients and harmful drinkers

Gil Leurquin-Sterk (BE) and Jenny Ceccarini (BE)
PET imaging of the glutamatergic and endocannabinoid systems in alcohol-dependent patients across the different stages of alcohol dependence

Emanuele Olivetti (IT)
Machine learning for high-dimensional hypothesis testing on neuroimaging data

Anne Beck (DE)
How neuroimaging may help to predict future relapse in alcohol-dependent patients: a focus on cue reactivity and possible clinical implications

Discussant: Andreas Heinz (DE)
Brain Circuitry Dysfunction in Fetal Alcohol Spectrum Disorders: Novel Mechanistic Insights from Animal and Human Studies

Chair: Fernando Valenzuela (US)
Co-Chair: Alberto Granato (IT)

Hermes H. Yeh (US)
Neuronal migration, circuit function and FASD:  toward a unified view of neurodevelopmental disorders

Olivier Pierrefiche (FR)
Disturbances of bidirectional synaptic plasticity in the hippocampus after moderate fetal alcohol exposure in rats.

Lee Anna Cunningham (USA)
Acute Oligodendrocyte Loss with Persistent White Matter Injury in a Third Trimester Equivalent Mouse Model of Fetal Alcohol Spectrum Disorder

James N. Reynolds (CA)
The relationship between white matter connectivity alterations and response inhibition deficits in children with Fetal Alcohol Spectrum Disorder

Discussant: Alberto Granato (IT)
Alcohol Induced Inflammation Links to Inter-Organ Crosstalk and Damage

Chair: Pranoti Mandrekar (US)
Co-Chair: Puneet Puri (US)

Ramon Bataller (US)
Systemic inflammation in alcoholic hepatitis: mechanisms and consequences

Hidekazu Tsukamoto (US)
Metabolic reprogramming drives cell fate regulation in alcoholic liver disease

Pranoti Mandrekar (US)
ER stress mediates adipose tissue inflammation during alcohol induced liver injury

Roberta Ward (BE)
Neuroinflammation after chronic and intermittent alcohol abuse

Discussant: Puneet Puri (US)
15.45-16.15
Coffee Break
16.15-17.45Targeting Neuron-Glial Interaction, Sleep and Energy Homeostasis for Novel Drug Development in Alcohol Use Disorder

Chair: Doo-Sup Choi (US)
Co-Chair: Daryl Davies (US)

Doo-Sup Choi (US)
Glutamate transporter EAAT2 and ethanol withdrawal in mice

Youssef Sari (US)
Effects of ceftriaxone on ethanol, nicotine or sucrose intake by alcohol-preferring (P) rats and its association with EAAT2 expression

Stephanie Perreau-Lenz (US)
Clock genes and sleep homeostasis: novel treatment targets in alcohol use disorders

Daryl Davies (US)
P2X4Rs within the brain dopamine (DA) reward system play an important role in the regulation of EtOH-intake 

Discussant: Mickael Naassila (FR)
Prospects for Imaging-Related Targets in Alcohol Use Disorders

Chair: Falk Kiefer (DE)
Co-Chair: Anna E. Goudriaan (NL)

Tess den Uyl (NL)
Effects of a combination of cognitive training and brain stimulation on physiological cue-reactivity in alcohol dependence

Patrick Bach (DE)
Genes, brain and behavior: the association between genetic markers in neurotransmitter systems and neural alcohol response

Anna E. Goudriaan (NL)
Neuroimaging and neurostimulation in alcohol dependence: a working mechanism study focusing on functional connectivity and emotion regulation

Joseph P. Schacht (US)
Alcohol cues and the ventral striatum: pharmacogenetic moderation of naltrexone effects and prediction of treatment response

Discussant: Raymond Anton (US)
Alcohol Consumption During Pregnancy: Evidence for Prevention

Chair: Tatiana Balachova (US)
Co-Chair: Ulrik Schiøler Kesmodel (DK)

Ulrik Schiøler Kesmodel (DK)
Alcohol Consumption During Pregnancy: Approaches to Prevention in the Nordic countries

Tatiana Balachova (US) and Galina Isurina (RU)
A brief physician intervention to reduce prenatal alcohol exposure: from formative evaluation to testing outcomes in community settings in Russia

Cristina D. Chambers and Claire Coles (US)
Resiliency Related Factors in Children Prenatally Exposed to Alcohol

Stefania Bazzo (IT)
Feasibility of an international communication campaign to raise awareness of Fetal Alcohol Spectrum Disorders

Discussant: Peggy Murray (US)
ESBRA-JMSAS Joint Symposium - Alcohol and Organ Damage

Chair: Tomasz Zima (CZ)
Co-Chair: Toshikazu Saito (JP)

Taro Takami (JP) and Isao Sakaida (JP)
Our liver regeneration therapies using autologous bone marrow-derived cells for liver cirrhosis: current status and prospects

Sachio Matsushita (JP)
Alcohol-induced brain damage associated with genetic variations

Helmut K. Seitz (DE)
Alcohol and colorectal cancer

Julia Mayerle (DE) Alcohol and pancreas

Discussant: Peter Eriksson (FI)
17.45-18.30
7th PLENARY LECTURE - DEDICATED TO ROGER NORDMANN

Emanuele Albano
(IT):
Oxidative stress and alcohol liver injury - Current view and future perspectives

Chair: Tomáš Zima (CZ)
20.00-....
Social Event URANIA
Science Slam and Finger Food , Award Ceremonies, Music “Bentgens und die MusikTiere”
TIMEPRECLINICAL CNSCLINICAL CNSHOT TOPICSALCOHOL-INDUCED ORGAN DAMAGE
9.00 - 10.30An Interdisciplinary and Translational Approach to Understanding the Role of GABA System in AUD

Chair: Rosana Camarini (BR)
Co-Chair: Peter Dodd (AU)

Roberto Ciccocioppo (IT)
Activation of PPARg attenuates alcohol drinking and exert potent antistress actions: Possible involvement of GABA-mediated mechanisms

Marisa Roberto (US)
Amygdalar GABAergic synapses: neuroadaptations induced by alcohol and stress

Fernando Valenzuela (US)
Developmental ethanol exposure impairs dentate gyrus GABAergic interneurons

Sung-Gon Kim (KR)
Effect of GABA Extract of Black Sticky Rice with Giant Embryo on Alcohol-Related Indices After Acute Alcohol Intake in Social Drinkers

Discussant: Peter Dodd (AU)
From Pleasure to Pain and Back Again: Alcohol and Nociception

Chair: Andrey Ryabinin (US)
Co-Chair: Marcin Wojnar (PL)

Marcin Wojnar (PL)
Reductions in physical pain predict lower risk of relapse following alcohol treatment

Andrzej Jakubczyk (PL)
Take control of your pain: physical pain and behavioural control in alcohol-dependent patients

Monique Smith (US)
I feel your pain: social transfer of alcohol-withdrawal induced hyperalgesia

Richard van Rijn (US)
Intricate involvement of delta opioid receptors in alcohol withdrawal induced hyperalgesia

Discussant: Andrey Ryabinin (US)
Sex and Gender Differences in Addiction Research

Chair: Carla Sanchis-Segura (ES)
Co-Chair: Jill Becker (US)

Jill B. Becker (US)
Sex Differences in Addiction: Preclinical Studies of Neural Mechanisms

Liana Fattore (IT)
Sex differences in compulsive behavior: emphasis on cannabinoids

Jill Hardee (US)
Sex differences in the development of emotion circuitry in adolescents at risk for substance use with an emphasis on alcohol

Flavia Franconi (IT)
Sex differences in side effects with drug abuse: pharmacokinetics and pharmacodynamics of drugs of addiction

Discussant: Marilyn Carroll (US)
Nordmann Award Symposium: Alcohol, Cardiovascular Disease and Nutritional Factors

Chair: Joaquim Fernández-Solà (ES)
Co-Chair: Roberta Ward (BE)

Joaquim Fernández-Solà (ES)
Detrimental effects of alcohol on cardiovascular system

Giovanni de Gaetano (IT)
Effects of alcohol at low dose in the context of a Mediterranean dietary pattern

Ramon Estruch Riba (ES)
Mediterranean diet in the primary prevention of cardiovascular disease

Rosa Lamuela (ES)
Polyphenols and cardiovascular risk

Discussant: Ramon Estruch Riba (ES)
10.30 - 10.45
Coffee Break
10.45 - 11.30
8th PLENARY LECTURE

Hans-Ulrich Wittchen
(Director, Institute of Clinical Psychology and Psychotherapy
Technical University Dresden):
The size and burden of AUD in comparison to other mental disorders in Europe

Chair: Jürgen Rehm (CA)
11.30 - 13.00Role of Alcohol-Induced Sensitization in Addiction: Genetics, and Interactions with Nicotine and the Environment.

Chair: Mickael Naassila (FR)
Co-Chair: Tamara Phillips (US)

Stephen Boehm (US)
Leveraging selectively bred mouse models to explore the genetic relationships between alcohol drinking, alcohol sensitization, and cocaine sensitization

Maria del Carmen Gonzales Marin (FR)
Vulnerability to ethanol sensitization predicts higher intake and motivation to self-administer ethanol

Tamara Phillips (US)
Nicotine effects on alcohol-induced sensitization and other traits: relevance to alcohol and nicotine coabuse

Rosana Camarini (BR)
Environmental enrichment vs exercise: ethanol sensitization vs CPP

Discussant: Mickael Naassila (FR)
Sexuality and Emotionality in Alcohol Dependence

Chair: Marcin Wojnar (PL)
Co-Chair: Jerzy Samochowiec (PL)

Aleksandra Krasowska (PL)
Alcohol-dependent sexual offenders

Geert Dom (BE)
Craving and negative affect: an Experience Sampling Method (ESM) study

Tilman Schulte (US)
Ignoring Emotion: Cue Reactivity and Negative Priming in Abstinent Alcoholics

Henri-Jean Aubin (FR)
The challenge of interpreting depressive symptoms in the context of an alcohol use disorder

Discussant: Jerzy Samochowiec (PL)
In Silico Predictions for Alcohol Use and Addiction

Chair: Klaus Obermayer (DE)
Co-Chair: Robert Whelan (IE)

Robert Whelan (IE)
Predicting alcohol binging and smoking in adolescents

Hamid Noori (DE)
Predicting alcohol drinking pattern in addicted rats

Sambu Seo (DE)
How structural and functional neuroimaging may predict future relapse in alcohol dependent patients

Michael A Rapp (DE)
Multivariate prediction of addiction severity and relapse using neurobiological and behavioral indicators

Discussant: Georgia Koppe (DE)
Alcohol Use Reduction Confer Reductions in Alcohol-Related Harm: Evidence from Clinical Trials, Epidemiological Data, Policy and Regulatory Perspectives

Chair: Karl Mann (DE)
Co-Chair: Katie Witkiewitz (US)

Jürgen Rehm (CA)
Alcohol Dependence and Alcohol Use Disorders: An Update on Prevalence and Associated Burden

Michael Bühlen (DE)
Regulatory (EMA) Guidance on Alcohol Dependence Medications

Deborah Hasin (US)
WHO Non-Abstinent Risk Categories in NESARC and Alcohol Dependence: A 3-Year Prospective Study

Katie Witkiewitz (US)
The Relationship of WHO Drinking Risk Categories to Health related Consequences: in Alcohol Clinical Trials

Discussant: Raymond Anton (US)
13.00 - 13.45
Lunch
13.45 - 14.30
9th PLENARY LECTURE

Norman Ohler
(DE): Breaking Bad: Hitler under Drugs

Chair: Rainer Spanagel (DE)
End of the Meeting
Opening of the German Society on Addiction Meeting 2016
Satellite symposia on Monday, September 5, 2016
14.30-17.30 E-med Meeting
(closed)
Satellite symposia on Tuesday, September 6, 2016
9.00-16.00 Sybil-AA Meeting - Horizon 2020
(closed)
Organizer: Wolfgang Sommer (DE) and Sandra Helinski (DE)
Please search for the entire abstract text here
The poster size is DIN A0, max. 120 cm high and 90 cm wide (Portrait format) and will have your Poster Number in the top left hand corner. Push pins will be available for your use.

NumberTitleAuthorsAffiliation
Preclinical CNS
1_1NEUROMEDIN U REGULATES ALCOHOL INTAKE AND ALCOHOL-INDUCED REWARD IN RODENTS VIA THE MESOLIMBIC DOPAMINE SYSTEMVallöf D, Kalafateli AL, Engel JA, Jerlhag EUniversity of Gothenburg, Sweden
1_2Fibroblast Growth Factor 2 (FGF2) is a Positive Regulator of Alcohol ConsumptionEven-Chen O, Shaham O, Barak SSchool of Psychological Sciences, Tel Aviv University, Israel
1_3ADOLESCENT INTERMITTENT ETHANOL REDUCES ADULT RAPHE NUCLEUS SEROTONERGIC NEURONS AND INCREASES INNATE IMMUNE EXPRESSION THAT IS PREVENTED BY EXERCISEVetreno RP, Crews FTUniversity of North Carolina at Chapel Hill, USA
1_4Effects of Ocimum sanctum Linn. in alcohol abstinence anxiety, depression and gene expression analysis in the amygdala of ratsGupta GL, Sharma A, Thakur ADepartment of Pharmacology, School of Pharmacy and Technology Management, SVKM’s NMIMS University, Mumbai-400 056, Maharashtra, India
1_5DYNAMICS OF ULTRASTRUCTURAL CHANGES IN THE FRONTAL CORTEX NEURONS OF RATS, EXPOSED TO ANTENATAL ALCOHOLBon EI, Zimatkin CMGrodno State Medical University, Grodno, Belarus
1_6A CANNABINOID RECEPTOR ANTAGONIST ATTENUATES GHRELIN-INDUCED ACTIVATION OF THE MESOLIMBIC DOPAMINE SYSTEM IN MICEKalafateli AL, Vallöf D, Heilig M, Engel AJ and Jerlhag EInstitute of Neuroscience and Physiology, Department of Pharmacology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
1_7SPICY FOOD PREFERENCE AND THE HPA AXIS REACTIVITY TO STRESS IN KOREAN SOCIAL DRINKERSJi-Hun Park, Sung-Gon Kim, Ji-Hoon Kim, Woo-Young Jung, Jin-Seong Lee, Won-Tan ByunPsychiatry, Pusan National University Yangsan Hospital, Yangsan, Korea
1_8EFFECT OF LUPANE TERPENOIDS ON SEVERITY OF ALCOHOL WITHDRAWAL IN RATSShlyahtun AH, Buben AL, Goncharuk VV, Satanovskaya VI, Kandyba NI, Ivanova A.A., Pronko PSInstitute of biochemistry of biologically active compounds, Grodno, Belarus
1_9Cocaine-induces conditioned place preference depending on adolescent exposure to ethanol and fat dietMateos-Garcia A, Blanco-Gandía MC, Reguilon MD, Arenas MC, Rodríguez-Arias M, Miñarro JDepartment of Psychobiology, School of Psychology, Universitat de València, Spain
1_10Ethanol rewarding effects in male mice are modulated by binge eating on a high-fat diet during adolescenceBlanco-Gandía MC, Montagud-Romero S, Ferrer-Pérez C, Aguilar MA, Miñarro J, Rodríguez-Arias MDepartment of Psychobiology, School of Psychology, Universitat de València, Spain
1_11?FosB INDUCTION IN ADOLESCENT AND ADULT RATS AFTER CHRONIC ETHANOL SELF-ADMINISTRATIONWille-Bille A, De Olmos S, Nizhnikov M, Marengo L, Pautassi, RMInstituto de Investigaciones Médicas Mercedes y Martín Ferreyra (INIMEC-CONICET-UNC), Argentina
1_12CONSEQUENCES OF SOCIAL DEFEAT STRESS ON BEHAVIORAL SENSITIZATION, ETHANOL REWARD AND CORTICOSTERONE LEVELSMacedo, GC; Favoretto, CA; Morita, G; Suchecki, D; Quadros, IMFederal University of São Paulo- UNIFESP Psychobiology Department- São Paulo, SP - Brazil
1_13ACUTE ALCOHOL ATTENUATES BUT DOES NOT ELIMINATE BOLD-STIMULATED FUNCTIONAL MRI RESPONSE IN RATSZahr NM, Müller-Oehring EA, Kwon D, Peterson ET, Sullivan EV, Pfefferbaum ASRI International and Stanford University School of Medicine, USA
1_14In vitro and in silico pharmacological characterization of the interaction between salsolinol and the µ-opioid receptor.Berríos-Cárcamo P, Quintanilla ME, Herrera-Marschitz M, Vasiliou V, Zapata-Torres G, Rivera-Meza MDepartment of Pharmacologic and Toxicologic Chemistry, Faculty of Chemical and Pharmaceuical Sciences, University of Chile, Chile
1_15ALDA-1 a pharmacological activator of the aldehyde dehydrogenase reduces alcohol consumption in alcohol preferring UChB rats.Rivera-Meza M, Vásquez D, Campanini J, Andrades J, Quintanilla ME, Herrera-Marschitz M, Israel YDepartment of Pharmacologic and Toxicologic Chemistry, Faculty of Chemical and Pharmaceuical Sciences, University of Chile, Chile
1_17The Nociceptin/Orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat modelsAbdul Maruf Asif Aziz, Shaun Brothers, Gregory Sartor, Markus Heilig, Claes Wahlestedt and Annika ThorsellLinköping University, Sweden
1_18CANNABINOIDE RECEPTOR 2 REGULATES THE EXPRESSION OF THE ALCOHOL REWARD PROPERTIES IN MICE CONDITIONNED PLACE PREFERENCEWarnault V & Valverde OPompeu Fabra University, Spain
1_19EFFECTS OF ETHANOL ACCESS IN A NURSING OR ISOLATED CONTEXT ON INTAKE IN ADOLESCENCEMiranda-Morales RS, Haymal OB, Pautassi RMInstituto Ferreyra (INIMEC-CONICET-Universidad Nacional de Córdoba), Argentina
1_20METABOLIC DISTURBANCES OF BRAIN HISTAMINERGIC NEURONS FOLLOWING ALCOHOL ADMINISTRATION IN RATSPhedina KM, Paulava DV and Zimatkin SMGrodno State Medical University, Belarus
Clinical CNS – Treatment – Translation – Neuroimaging
2_1Occipital event-related potentials to addiction-related stimuli in detoxified patients with alcohol dependence. Association with three-month relapseMüller BW, Matheus-Roth C, Schenk I, Scherbaum NClinic for Psychiatry and Pyschotherapy, LVR-Hospital, University of Duisburg-Essen, Germany
2_2Mobile technology targeting concurrent alcohol and drug use in HIV+ adults: A PILOT STUDYAharonovich E, Cannizarro D, Derri J, Lee A, Stohl M, Hasin DNew York State Psychiatric Institute / Columbia University Medical Center, USA
2_3Abnormal resting-state functional connectivity in the orbitofrontal cortex of heroin users and its relationship with anxiety: a pilot fNIRS studyIeong FH, Yuan ZUniversity of Macau, China
2_4TLR4 METHYLATION MODERATES THE RELATIONSHIP BETWEEN ALCOHOL USE SEVERITY AND GRAY MATTERKaroly, HC, Thayer RE, Hagerty SL, & Hutchison, KEUniversity of Colorado Boulder, USA
2_5Altered resting state functional connectivity between the insula and DMN region reflects duration of illness in gambling disorder patientsTsurumi K, Aso T, Kawada R, Hazama M, Miyata J, Fukuyama H, Murai T, Takahashi HDepartment of Psychiatry, Graduate School of Medicine, Kyoto University, Japan
2_6ALTERED REGIONAL FUNCTIONAL CHANGES IN INTERNET GAMING DISORDER and alcohol use disorder: 18F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY STUDYKim H, Kim YK, Nam CR, Lim JA, Kim DJ, Choi JSDepartment of Psychiatry, Seoul National University, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea
2_7ALCOHOL AND AGE EFFECTS ON RESPONDING TO AND IGNORING STIMULI IN A DRIVING SIMULATORPrice JL, Reaves SA, Boissoneault J, Frazier IR, Nixon SJUniversity of Florida, USA
2_8Comprehensive neuropsychological profiles for Internet gaming disorder (IGD), Alcohol use disorder (AUD) and Obsessive-compulsive disorder (OCD)Lim JA, Nam CR, Lee JY, Choi AR, Kim YJ, Kim DJ, Kim SN, Kwon JS, Choi JSDepartment of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea
2_9A ROLE OF RESILIENCE IN INTERNET ADDICTION AMONG ADOLESCENTS DIFFERING BETWEEN GENDERS : A MODERATED MEDIATION MODELNam CR, Lee JY, Choi AR, Lim JA, Kim YJ, Kim DJ, Choi JSDepartment of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea
2_10POST-ABSTINENCE RESPONSE DRINKING IN HUMANS – SEX DEPENDENT?Plawecki MH, Kosobud A, Vitvitskiy V, Grahame N, Millward J, Haines J, Hays J, Shehkar S, Nurnberger JN, Kareken D, Crabb D, and O’Connor SJIndiana University School of Medicine, Indianapolis IN, USA
2_11SAFETY AND EFFICACY OF VARENICLINE IN PATIENTS WITH SEVERE ALCOHOL DEPENDENCEPfeifer P, Warnke S, Kaiser AK, Fehr CUniversity Hospital of Psychiatry Bern, Bern, Switzerland
2_12VALIDATION OF A TEST SYSTEM FOR DEVELOPMENT OF MEDICATIONS FOR ALCOHOLISM (TEMA)Spreer M, Smolka MN, O'Connor S, Plawecki MH, Zimmermann USDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
2_13THE SUBJECTIVE RESPONSE TO NITROUS OXIDE IS A POTENTIAL PHARMACO-ENDOPHENOTYPE FOR ALCOHOL USE DISORDERKamboj SK, Walsh K, Das RKUniversity College London, UK
2_14METHODOLOGICAL AND PRACTICAL APPROACH FOR PHARMACOLOGICAL TREATMENT PERSONALIZATION IN ALCOHOL USE DISORDERSVignoli T, Caputo FDepartment of Addiction and Mental Health, Italy
2_15A pharmacokinetic and dynamic study of the GABA-B receptor system in alcohol dependenceTurton S, Durant C, Nahar LK, Cordero RE, Paterson S, Nutt D, Wilson S, Lingford-Hughes ACentre for Neuropsychopharmacology, Department of Medicine, Imperial College London, UK
2_16Striatal Reward Sensitivity as a Neurobiological Marker Informing Therapy-Related Neural Changes in Alcohol Use DisorderBecker A, Gerchen MF, Kirsch M, Hoffmann S, Kiefer F, Kirsch PDepartment of Clinical Psychology, Central Institute of Mental Health, Medical Faculty Mannheim / Heidelberg University, Germany
2_17FUNCTIONAL REWARD PROCESSING IN ALCOHOL DEPENDENCE DURING A SLOT MACHINE PARADIGMPelz P, Beck A, Lorenz RC, Charlet K, Geisel O, Banas R, Heinz A, Müller CACharité - Universitätsmedizin Berlin, Germany
2_18EXISTENTIAL NEUROSCIENCE: IMPAIRED WHITE MATTER IS LINKED WITH INSECURE ATTACHMENT IN POLY DRUG USEHiebler-Ragger M, Unterrainer HF, Koschutnig K, Fuchshuber J, Tscheschner S, Url M, Wagner-Skacel J, Papousek I, Weiss EM, Fink AUniversity Clinic of Psychiatry, Medical University Graz, Austria
2_19TEMPORAL STABILITY OF THE LATENT FACTOR STRUCTURE OF SUBJECTIVE ALCOHOL RESPONSESLutz, J; Childs, EUniversity of Illinois at Chicago, USA
2_20DOES SELF-REPORTED OR BEHAVIORAL IMPULSIVITY PREDICT SUBJECTIVE RESPONSE TO LOW DOSE ALCOHOL?Berey, BL, Leeman, RF, Pittman, B, Franco, N, Krishnan-Sarin, SUniversity of Florida, USA
2_56FINDING THE OPTIMAL TREATMENT MODEL: A SYSTEMATIC REVIEW OF INTERVENTIONS FOR TREATING CO-OCCURRING ALCOHOL MISUSE AND DEPRESSIONHobden B, Bryant J, Sanson-Fisher R, Baker A, Mattick R, Shakeshaft A, Farrell MUniversity of Newcastle, Australia
2_58TRAINING INHIBITION IN ADDICTIVE DISORDERS: A PILOT STUDY. RATIONALE, METHODS AND PRELIMINARY DATALuquiens Amandine, Miranda Ruben, Carré Arnaud, Aubin Henri-JeanDépartement de psychiatrie et d’addictologie, Hôpital Paul Brousse, University of Paris-Saclay, University of Paris-Sud, UVSQ, CESP, INSERM U 1178, APHP Villejuif, France
Genetics – Diagnosis – FASD – Hot Topics
3_1INDEPENDENT AND EPISTATIC INTERACTIONS BETWEEN GENETIC VARIANTS OF OPRM1 AND DAT1 ON ALCOHOL CONSUMPTION AND SUBJECTIVE RESPONSES IN SOCIAL DRINKERSWeerts EM, Wand GS, Maher B, Xu X, Stephens MA, Yang X, and McCaul MEJohns Hopkins University, USA
3_3Biodiversity Strikes Again; Using Underlying Polymorphisms to Benefit Treatment. Treatment of MDD Patients with MTHFR Polymorphisms and Low RBC Membrane Omega-3 Fatty Acids with a Combination of Methylated B Vitamins and Omega-3 Fatty Acids.Arnold MechMech Healthcare Associates, USA
3_4INVESTIGATING THE ROLE OF ONE-CARBON METABOLISM PATHWAY IN COMPLICATED ALCOHOL WITHDRAWAL STATESKulkarni KR, Purushottam M, Sharma P, Viswanath B, Chand P, Jain S, Murthy PNational Institute of Mental Health & Neurosciences, Bangalore, India
3_5EXPLORATORY STUDY ON DRINKING PATTERN AND POLYMORPHISM OF ALDH2 IN HEALTHY JAPANESE MEN WITH DRINKING HABITSKamada Y, Sekiguchi N, Kitagawa YSafety Science Institute, Suntory Business Expert Limited, Kyoto, Japan
3_6CORRELATION BETWEEN BLOOD ACETALDEHYDE CONCENTRATION AND HEART RATE CHANGE IN YOUNG JAPANESE ADULTS WITH DIFFERENT ALDH2 GENOTYPESToyama T, Matsushita S, Hara S,Ogawa M, Tsukahara M, Kotake M, Roh S, Higuchi SKurihama Medical and Addiction Center, Japan
3_7Roles of the ADH1B and ALDH2 genotypes in alcohol expectancy among patients with alcohol dependenceItoh M, Yonemoto T, Mihara S, Toyama T, Yumoto Y, Iwahara C, Takimura T, Sakuma H, Nakayama H, Komoto Y, Maesato H, Kimura M, Matsushita S, Higuchi SNational Hospital Organization Kurihama Medical and Addiction Center, Japan
3_8DNA METHYLATION LINKS ALCOHOL USE TO ALTERNATIVE PROMOTER USE IN SYNAPTIC GENESCervera-Juanes R, Wilhem LJ, Huang C, Shah R, Gonzales S, Grant KA, Ferguson BOregon Primate Research National Center, Oregon Health and Science University, USA
3_9VGLUT2 GENOTYPE INTERACTS WITH ENVIRONMENTAL EXPERIENCES TO PREDICT ALCOHOL MISUSE IN YOUNG ADULTSVrettou, M, Nilsson, KW, Tuvblad, C, Rehn, M, Andershed, AK, Wallén-Mackenzie, Å, Andershed, H, Nylander, I, Comasco, EDepartment of Neuroscience, Uppsala University, Uppsala, Sweden
3_10GENETIC OVERLAP BETWEEN IMPULSIVITY AND ALCOHOL DEPENDENCE: A LARGE-SCALE NATIONAL TWIN STUDYLotfi Khemiri, Ralf Kuja-Halkola, Henrik Larsson, Nitya Jayaram-LindströmKarolinska Institutet, Stockholm, Sweden
3_11Genetically Controlled Epigenetic Mechanisms of Neuropeptide Transcription in Alcoholic Human BrainBazov I, Kononenko O, Sarkisyan D, Watanabe H, Stålhandske L, Yakovleva T, Bakalkin GUppsala university, Sweden
3_12ASSOCIATION ANALYSIS OF BRAP POLYMORPHISMS ON THE RISK OF ALCOHOL DEPENDENCE AND ALCOHOL USE DISORDERS IDENTIFICATIONS TEST (AUDIT)Shin JG, Kim JW, Lee BC, Choi IGHallym University, Seoul, Korea (South)
3_13Association Study of GABRA2 and GRIN2B polymorphisms in Alcohol DependenceBhagyalakshmi Shankarappa; Shwetha Byrappa; Rashmi Chandra; Meera Purushottam; Biju Viswanath; Sanjeev Jain; Pratima MurthNational Institute of Mental Health and Neurosciences, India
3_14An Endo-phenotype Approach to the Genetics of Alcohol Dependence: A Genome Wide Association Study of Fast Beta EEG in Families of African AncestryJacquelyn Meyers et al.State University of New York Downstate Medical Center; Columbia University, USA
3_15Increasing alcoholic patients with homozygous for the ALDH2*2 gene allele in Japan: case reportsUeno F, Yumoto Y, Yonemoto T, Ito M, Kimura M, Yokoyama A, Matsushita S, Higuchi SNational Hospital Organization Kurihama Medical and Addiction Center, Japan
3_16DRD2 METHYLATION ASSOCIATED WITH EXECUTIVE CONTROL NETWORK CONNECTIVITY, AND CLINICAL OUTCOMES OF ALCOHOL USE DISORDER SEVERITY AND IMPAIRED CONTROLHagerty SL, Bidwell LC, YorkWilliams S, Hutchison KEUniversity of Colorado Boulder, USA
3_17INTERACTION OF MAOA GENOTYPE, DNA METHYLATION AND STRESSFUL LIFE EVENTS IN RELATION TO ALCOHOL MISUSEBendre M, Checknita D, Tiihonen J, Hodgins S, Comasco E, Nilsson KWDepartment of Neuroscience, Uppsala University, Uppsala, Sweden
3_18DRD2 PROMOTER METHYLATION DEMONSTRATES CONSSITENCY ACROSS TISSUE TYPE AND IS ASSOCIATED WITH BOLD RESPONSE TO ALCOHOL CUESBIDWELL, LC, WEILAND, B, BRYAN, AD, HUTCHISON, KEUniversity of Colorado, USA
Alcohol-induced organ damage
4_1A Unifying Hypothesis Linking Ethanol-Induced Mitochondrial Depolarization to Mitophagy and the Proinflammatory and Early Profibrotic Events in Alcoholic Liver DiseaseZhong Z, Rehman H, Liu Q, Krishnasamy Y, Ramshesh VK, Mittler CS, Lemasters JJMedical University of South Carolina, USA
4_2SUB-CHRONIC ETHANOL EXPOSURE SENSITIZES THE LIVER TO IMIQUIMOD-INDUCED INFLAMMATORY RESPONSE IN MICEMassey VL, Qin L, Crews FTUniversity of North Carolina at Chapel Hill, USA
4_3ALCOHOL BLUNTS PKA-DEPENDENT PHOSPHORYLATION OF SEVERAL PROTEINS KEY TO THE REGULATION OF AIRWAY CILIA MOTILITYPrice ME, Simet SS, Pavlik JA, and Sisson JHUniversity of Nebraska Medical Center, USA
4_4HEPATOPROTECTIVE AND ANTI-INFLAMMATORY EFFECTS OF PENTOXIFYLLYNE AND ITS COMBINATION WITH BETAINE IN EXPERIMENTAL ALCOHOLIC STEATOHEPATITISBuko V, Lukivskaya O, Naruta E, Belanovskaya EInstitute of Biochemistry of Biologically Active Compounds, Grodno, Belarus
4_5PATHOGENESIS OF MALONDIALDEHYE-ACETALDEHYDE PROTEIN ADDUCT-MEDIATED INJURY IN LUNGWyatt TA, Burnham EL, Kharbanda K, Thiele GM, Sisson JHUniversity of Nebraska Medical Center, Omaha, NE, USA
4_6THE MENSTRUAL CYCLE INFLUENCES THE GASTRIC EMPTYING OF ALCOHOLKaibara N, Horikoshi M, Miyasaka KTokyo-Kasei University; Japan
4_7MODERATE ALCOHOL CONSUMPTION DECELERATES THE DEVELOPMENT OF CARBOHYDRATE-INDUCED NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) IN MICEEngstler AJ, Kanuri G, Priebs J, Bergheim IInstitute of Nutritional Sciences, S.D. Model Systems of Molecular Nutrition, Friedrich-Schiller-University Jena, Germany
4_8EFFECT OF CHRONIC BEER INGESTION ON THE DEVELOPMENT OF ALCOHOL-INDUCED LIVER DAMAGE. STUDIES IN MICEJung, F, Engstler AJ, Brandt A, Sellmann C, Jin CJ, Bergheim IInstitute of Nutritional Sciences, S.D. Model Systems of Molecular Nutrition, Friedrich-Schiller-University Jena, Jena, Germany
4_9MICRO-RNAs (34a*, 122, 126* and 155) LEVELS IN THE PLASMA OF PATIENTS SUFFERING FROM ALCOHOLIC LIVER DISEASEPapillon C-A, Buttolo R, Sava M, Naassila M, Nguyen-Khac E, Houchi HGRAP INSERM ERi24, France
4_10THE PHYSICAL AND MENTAL COMORBIDITY IN ALCOHOL ABUSE AND DEPENDENCE: A DIFFERENT PERSPECTIVEZhao ZR, Ong HS, Cheok CS, Guo SInstitute of Mental Health, Singapore
NumberTitleAuthorsAffiliation
Preclinical CNS
1_16BENZODIAZEPINE-GABAA ?1 ANTAGONIST 3-ISO-PBC SELECTIVELY REDUCES ALCOHOL SELF-ADMINISTRATIONWeerts EM, Holtyn AF, Tiruveedhula VVNPB, Cook JMJohns Hopkins University School of Medicine, USA
1_21ENVIRONMENTAL ENRICHMENT DIFFERENTIALLY MODULATES SOCIAL AND REWARD PROCESSES: INVOLVEMENT OF THE OXYTOCINERGIC SYSTEMRae, MB; Zanos, P, Georgiou, P, Bailey, A, Camarini RDepartment of Pharmacology - USP/ São Paulo-Brazil
1_22NOVEL MOUSE MODEL OF ALCOHOL DRINKING BEHAVIOR IN SOCIAL CONTEXT: INTELLICAGE APPLICATIONKoskela M, Voikar V, Airavaara MInstitute of Biotechnology, University of Helsinki, Finland
1_23PROINFLAMMATORY SIGNALING REGULATES VOLUNTARY ALCOHOL INTAKE AND STRESS INDUCED CONSUMPTION AFTER EXPOSURE TO SOCIAL DEFEAT STRESS IN MICEKarlsson C, Schank JR, Rehman F, Stojakovic A, Björk K, Barbier E, Solomon M, Tapocik JD, Engblom D, Thorsell A, Heilig MLinkopings University, Sweden
1_24DEPENDENCE-INDUCED INCREASE OF ALCOHOL SELF-ADNINISTRATION AND COMPULSIVE DRINKING MEDIATED BY THE HISTONE METHYLTRANSFERASE PRDM2Barbier E, Johnstone AL, Khomtchouk BB, Tapocik JD, Pitcairn C, Rehman F, Augier E, Borich A, Schank JR, Rienas CA, Van Booven DJ, Sun H, Nätt D , Wahlestedt C, Heilig MDepartment of Clinical and Experimental Medicine, Division of Cell Biology, Faculty of Health Sciences, Linköping University, Sweden
1_25STYDYING EFFECTS OF TRACE AMINE-ASSOCIATED RECEPTOR 1 ACTIVATION ON DOPAMINE RELEASEBudygin EA, Hoener MCWake Forest School of Medicine, Winston-Salem, USA
1_26EFFECTS OF ETHANOL ON SOCIAL AVOIDANCE INDUCED BY CHRONIC SOCIAL DEFEAT STRESSFavoretto CA, Macedo GC, Quadros IMFederal University of São Paulo (UNIFESP), Brazil
1_27ETHANOL INTAKE AFTER AAV VIRAL VECTOR-MEDIATED OVEREXPRESSION OF PALLIDAL µ-OPIOID RECEPTORSUhari-Väänänen J, Ylitalo M, Koskela M, Harvey BK, Oinio V, Raasmaja A, Airavaara M, Piepponen P, Kiianmaa KUniversity of Helsinki, Faculty of Pharmacy, Division of Pharmacotherapy, Helsinki, Finland
1_28ORBITOFRONTAL CORTEX MEDIATES CONTEXT-INDUCED RELAPSE TO ALCOHOL.Leão RM, Bianchi PC, Palombo P, Carneiro-de-Oliveira PE, Planeta CS, Cruz FCDepartamento de Biorregulação, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, BA 40110-902, Brazil
1_29ROLE OF AMYGDALA NEURONAL ENSEMBLES IN CONTEXT-INDUCED REINSTATEMENT OF ALCOHOL SELF-ADMINISTRATION IN RATSCruz FC, Bianchi PC, Palombo P, Carneiro-de-Oliveira PE, Planeta CS, Leão RMPharmacology Department, São Paulo Federal University, Brazil.
1_30Chemogenetic inactivation of midbrain dopamine neurons and their projections to the nucleus accumbens attenuates alcohol-seeking behaviourValyear MD, Trujillo-Pisanty I, Lacroix F, Shizgal P, Chaudhri NConcordia University, Canada
1_31HISTOLOGICAL CHANGES IN THE CEREBELLUM 45-DAYS OLD RATS AFTER PRENATAL ALCOHOL EXPOSUREPukhov DN, Sakel VVGrodno state medical university, Grodno, Belarus
1_32Prenatal alcohol exposure (PAE) impairs pattern separation in a touchscreen assay sensitive to alterations in hippocampal neurogenesisKenton, JA, Josey, M, Carrica, L, Cunningham, Lee Anna & Brigman, JLUniversity of New Mexico, USA
1_33ROLE OF PRELIMBIC CORTEX MEDIATES CONTEXT-INDUCED THE REINSTATEMENT OF ALCOHOL-SEEKING.Palombo P, Bianchi PC, Leão RM, Carneiro-de-Oliveira PE, Planeta CS, Cruz FCUNESP, Brazil
1_34CEREBELLAR NEURODEVELOPMENT IN RATS PRENATALLY EXPOSED TO ALCOHOLSukhadolski PA, Zimakin SMGrodno state medical university, Grodno, Belarus
1_35ROLE OF ACCUMBENS CORE IN CONTEXT-INDUCED REINSTATEMENT OF ALCOHOL-SEEKING IN RATSBianchi PC, Leão RM, Palombo P, Carneiro-de-Oliveira PE, Tavares, LC, Planeta CS, Cruz FCSão Paulo State University UNESP, Brazil
1_36SHORT-TERM ENVIRONMENTAL ENRICHMENT REDUCES THE CORTICOSTERONE RESPONSE FOLLOWING ACUTE RESTRAINT STRESS BUT NOT AFTER ETHANOL TREATMENTRueda, AV, Amaral, BH, Rae, MB, Marianno, P, Costa, GA, Carrara-Nascimento, PF, Camarini, RUniversidade de São Paulo - Brazil
1_37THE INTRA-pVTA ADMINISTRATION OF ETHANOL INDUCES DOSE-DEPENDENT CONDITIONED PLACE PREFERENCE IN WISTAR RATSCampos-Jurado Y, Hipolito L, Bahilo A, Cano-Cebrián MJ, Polache A, Granero L, Zornoza T, Martí-Prats LUniversitat de València, Spain
1_38MESOCORTICOLIMBIC SYNCHRONY IS ALTERED IN SELECTIVELY BRED ALCOHOL PREFERRING VERSUS OUTBRED RATS ENGAGED IN A CUED ALCOHOL DRINKING TASKMcCane AM, Ahn S, Rubchinsky L, Janetsian SS, Linsenbardt DN, Czachowski CL and Lapish CLIndiana University Purdue University Indianapolis, USA
1_39EFFECTS OF CHRONIC ALCOHOL DRINKING ON CIRCADIAN GENE EXPRESSIONBatish T, Kanadibhotla S, Firsick E, Powell S, Hack W, Schlumbohm J, Crabbe JC, Ozburn AROregon Health & Science University, USA
1_40THE MGLUR2 POSITIVE ALLOSTERIC MODULATOR, AZD8529 SPECIFICALLY BLOCKS CUE-INDUCED RELAPSE TO ALCOHOL-SEEKING IN RATSAugier E, Dulman RS, Rauffenbart C, Augier G , Cross AJ, and Heilig MCenter for Social and Affective Neuroscience, IKE, Linköping University, Sweden
1_61Sex and gender in addiction research: Separate or mix with care? Carla Sanchis-SeguraArea de Psicobiologia. Universitat Jaume I. Castelló. Spain
Clinical CNS – Treatment – Translation – Neuroimaging
2_21BRAIN REGIONAL MGLUR5 AVAILABILITY IN RECREATIONAL AND DEPENDENT COCAINE USERSScala SG, Milella M, Fotros A, Larcher K, Dagher A, Rosa-Neto P, Benkelfat C, & Leyton MMcGill University, Canada
2_22DISTINCT NEURAL CORRELATES OF RISK-TAKING AND HEAVY ALCOHOL USE IN EMERGING ADULTHOODYorkWilliams SL, Thayer RE, Hagerty SL, Bidwell LC, Hutchison KEUniversity of Colorado Boulder, USA
2_23WHITE AND GRAY MATTER ASSOCIATIONS WITH ALCOHOL PROBLEMS AMONG HIGH-RISK YOUTHThayer RE, YorkWilliams S, Feldstein Ewing S, Bryan AD, Hutchison KEUniversity of Colorado Boulder, USA
2_24ACUTE EFFECT OF INTRAVENOUSLY APPLIED ALCOHOL IN THE HUMAN STRIATAL AND EXTRASTRIATAL D2/D3 DOPAMINE SYSTEMPfeifer P, Tüscher O, Buchholz HG, Gründer G, Vernaleken I, Paulzen M, Zimmermann US, Maus S, Lieb K, Eggermann T, Schreckenberger M, Fehr CDepartment of Psychiatry, Psychotherapy and Psychosomatics, Agaplesion Markus Hospital, Frankfurt am Main, Germany
2_25The effect of non-alcoholic beverages on the outcome of alcoholics after hospitalized treatmentKimura M, Yoshimura A, Yoneda J, Maesato H, Takimura T, Nakayama H, Sakuma H, Toyama T, Yokoyama A, Matsushita S, Higuchi SNational Hospital Organization, Kurihama Medical and Addiction Center, Japan
2_26ALCOHOL DEPENDENT PATIENTS WITH A HISTORY OF MOOD DISORDER HAVE GREATER HPA AXIS DYSREGULATION AND RAISED INTERFERON-ALPHA DURING ALCOHOL WITHDRAWALNewson MJ, Gilmour A, Cherian R, Muhammed N, Dar K, Rabiner EA, Cavanagh J, McInnes IB, Lingford-Hughes AR & Kalk NJAddictions Department, Kings College London, London, United Kingdom
2_27WHAT IMPACT DOES INDIVIDUALISM AND COLLECTIVISM HAVE ON THE RELATIONSHIP BETWEEN IMPULSIVITY AND NEGATIVE CONSEQUENCES DUE TO DRINKING?Schwebel, F J, Larimer, M E, Lee, C M, Lewis, M, Berglund, M, & Andersson, CUniversity of Washington, Department of Psychology, USA
2_28A population pharmacokinetic-pharmacodynamic study of anticraving effect of baclofen in alcohol-dependent patients.SIMON N, IMBERT B, ALVAREZ JCUniversity Hospital of Marseille, France
2_29FUNCTIONAL BRAIN CONNECTIVITY IN ALCOHOL DEPENDENT PATIENTS: INFLUENCE OF NALTREXONE-TREATMENTWeil G, Cecile Bordier, Sabine Vollstädt-Klein, Derik Hermann, Falk Kiefer, Angelo Bifone, Wolfgang H. SommerDepartment of Addiction Medicine and Addictive Behavior, Central Institute of Mental Health, University of Heidelberg, Germany
2_30BALANCING RISK AND BENEFIT IN HEAVY DRINKERS TREATED WITH TOPIRAMATE: IMPLICATIONS FOR PERSONALIZED CAREKranzler HR, Feinn R, and Curtis BUniversity of Pennsylvania Perelman School of Medicine, USA
2_31VIRTUAL MORRIS TASK RESPONSES IN ALCOHOLICS DURING WITHDRAWALCarito V, Ceccanti M, Coriale G, Messina MP, Fiore MInstitute of Cellular Biology and Neurobiology, National Research Council (CNR), Rome, Italy
2_32MODEL-BASED LEARNING AS A FUNCTION OF VALENCE: PRESYNAPTIC DOPAMINE, MU-OPIOID RECEPTOR AND SEROTONIN TRANSPORTER DENSITYVoon V, Joutsa J, Kaasinen VUniversity of Cambridge, UK
2_33ACCEPTABILITY OF A VIRTUAL INTERVENTION TO ALCOHOL MISUSERS IN BRAZIL: AN EXPLORATORY STUDYAndrade ALM, Bedendo AS, Sartes LM, Souza-Formigoni MLOUniversidade Federal de Sao Paulo, Brazil
2_34Gender differences in affects and craving in alcohol-dependence: A study during protracted alcohol withdrawalGéraldine Petit; Olivier Luminet; Mariana Cordovil de Sousa Uva, Pauline Monhonval, Sophie Leclercq; Pierre Maurage; Philippe de TimaryUniversité Catholique de Louvain, Louvain-la-Neuve, Belgium
2_35NK1 ANTAGONISM ATTENUATES BLUNTED RESPONSE TO MONETARY REWARD ANTICIPATION IN ABSTINENT ALCOHOL BUT NOT POLYDRUG DEPENDENT INDIVIDUALSPaterson LM, McGonigle J, Murphy A, Elliott R, Ersche KD, Flechais R, Orban C, Smith DG, Suckling J, Taylor EM, Deakin JFW, Robbins TW, Nutt DJ, Lingford-Hughes AR, ICCAM PlatformImperial College London, UK
2_36ADHD AND ALCOHOL ADDICTION – AN FMRI STUDY, USING A COMBINED CUE REACTIVITY AND INHIBITION PARADIGMM Luderer, E Sobanski, G Meyer zu Schwabedissen,R Nuriyeva, J Seidt, O Hennig, B Alm, D Hermann, WH Sommer, F Kiefer, S Vollstädt-KleinDepartment of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany
2_37ADHD AND ALCOHOL ADDICTION – COMMONALITIES AND DIFFERENCES IN MOVEMENT PATTERNS DURING A CONTINUOUS PERFORMANCE TASK (CPT)M Luderer, S Vollstädt-Klein, J Seidt, R Nuriyeva, G Meyer zu Schwabedissen, S Lis, O Hennig, B Alm, D Hermann, WH Sommer, F Kiefer, E SobanskiDepartment of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany
2_38DEEP BRAIN STIMULATION IN 4 PATIENTS WITH TREATMENT RESISTANT ALCOHOL ADDICTIONM Luderer, M Jakobs, UJ Mueller, WH Sommer, J Kuhn, B Bogerts, K Kiening, K MannDepartment of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany
2_39A CENTRAL ROLE OF SELF-CONSCIOUSNESS ON THE RELATION BETWEEN DEPRESSION AND CRAVING IN ALCOHOL-DEPENDENT MEN AND WOMEN: A STUDY DURING ALCOHOL-WITHDRAWALPoncin M, Vermeulen N, Leclercq S, Maurage P, de Timary PUniversité Catholique de Louvain, Louvain-la-Neuve, Belgium
2_40REGIONAL CEREBRAL BLOOD FLOW ALTERATIONS IN BUPRENORPHINE MAINTAINED OPIOID ADDICTS AND THEIR RELATIONSHIPS TO COGNITION AND CIGARETTE SMOKINGMeyerhoff DJ, Murray D, Schmidt TL, Murray T, Durazzo TC, Guydish GUniversity of California, San Francisco, USA
Genetics – Diagnosis – FASD – Hot Topics
3_19Psychiatric comorbidity and severity of Alcohol Use Disorder (AUD)Coriale G, Fiore M, Fiorentino D1, Battagliese G, De Rosa F, Porrari R, Pisciotta F, Ledda R, Gencarelli S, Ceccanti MCenter for Alcohol Abuse (Centro Riferimento Alcologico Regione Lazio-CRARL, Department of Clinical Medicine, Sapienza University of Rome, Italy
3_20ALCOHOL-INDUCED VITAMIN A DEFICIENCY: CHARACTERIZATION OF FAS-LIKE CRANIOFACIAL MALFORMATIONS IN A NOVEL FASD MOUSE MODELPetrelli B, Oztu?rk A, Pind M, Fainsod A, and Hicks GGUniversity of Manitoba, Canada
3_21examination of Maternal alcohol and other risk factors across trimester in a large ethnically diverse sample from a Perinatal Support ProgramOnoye, J, Pascal, E, Hayes, D, Thompson, MUniversity of Hawaii, USA
3_22DETECTABLE BLOOD CONCENTRATIONS OF PHOSPHATIDYLETHANOL (PETH) IN STUDY PARTICIPANTS CONSUMING ONE GLASS OF WINE/DAY FOR ONE WEEKWalther L, Stenton J, Hansson T, Andersson A, Blomgren A, Isaksson ADivision of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, University Hospital, Lund University, Lund, Sweden
3_23ALTERATION OF DNA METHYLATION PROGRAM IN THE PRENATAL ETHANOL-INDUCED THINNING CORTICESÖztürk NC, Marisol Resendiz M, Zhou FCIndiana University School of Medicine; USA
3_24CHILDHOOD PLACEMENT IN OUT-OF-HOME CARE IN RELATION TO PSYCHOSOCIAL OUTCOMES IN ADULTS WITH FETAL ALCOHOL SYNDROMERangmar, J, Dahlgren Sandberg, A, Aronson, M and Fahlke, CDepartment of Psychology, University of Gothenburg, Sweden
3_25Validation of Alcohol Use Disorders Identification Test short version (AUDIT-C) among Spanish college students.Busto Miramontes A, Corral M, Carbia C, Rodríguez Holguín S, Caamano Isorna F, Cadaveira F1. Public Health. Universidade de Santiago de Compostela. CIBER-ESP. Spain. 2. Preventive Medicine. University Hospital of Ourense. Spain
Alcohol-induced organ damage
4_11Blocking of IL-17A signaling attenuate alcohol induced steatohepatitis and liver fibrosisXu, J, Lan, T, Liu, X, Brenner, DA and Kisseleva, TDepartment of Medicine, UC San Diego, USA
4_12Stearoyl-CoA desaturase in alcoholic liver fibrosis and cancerLai KKY, Kweon SM, Chi F, Hwang E, Kabe Y, French S3, Murali R, Ntambi JM, Tsukamoto HSouthern California Research Center for ALPD and Cirrhosis, USA
4_13THE MECHANISM OF ALCOHOL-INDUCED GOLGI FRAGMENTATION IN HEPATOCYTESPi-Wan Cheng, Carol A. Casey and Armen PetrosyanDepartment of Biochemistry and Molecular Biology, College of Medicine, and 2Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA
4_14DIFFERENTIAL ROLE FOR THE TRANSCRIPTIONAL AND NON-TRANSCRIPTIONAL FUNCTIONS OF IRF-3 IN CHRONIC ETHANOL-INDUCED LIVER INJURYSanz-Garcia C, Roychowdhury S, Chattopadhyay S, McMullen MR, Sen GC, Nagy LEDepartment of Pathobiology, Center for Liver Disease Research, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA
4_15HEPATIC STELLATE CELLS REGULATE CCR2 MRNA STABILITY AND RECRUITMENT OF INFLAMMATORY CELLS VIA NOX4 IN ALCOHOLIC LIVER INJURYDehnad A, Sasaki Y, Jiang JX, Sato A, Chao TI, Tian J, Török NJDivision of Gastroenterology and Hepatology, University of California Davis, Sacramento, CA, USA
4_16CARDIOVASCULAR DISEASE BURDEN, LIVER FUNCTION, AND FIBROBLAST GROWTH FACTOR-23 IN ALCOHOLIC PATIENTSQuintero-Platt G, González-Reimers E, Rodríguez-Gaspar M, de la Vega-Prieto MJ, Martín-González C, Pérez-Hernández O, Romero-Acevedo L, Santolaria-Fernández FServicio de Medicina Interna, Hospital Universitario de Canarias. Tenerife, Canary Islands, Spain.
4_17ROLES OF HIGH KM ADH3 IN INCREASE IN ALCOHOL METABOLISM BY CHRONIC ALCOHOL?CONSUMPTION AND IN PROGRESSION OF ALCOHOLIC LIVER DISEASEHaseba T, Maruyama M, AkimotoT, Naruo M, and OkudaTNippon Medical School, Japan
4_18TLR7 signaling negatively regulates the progression of mouse model of alcoholic hepatitisMichael Pimienta, Hiroshi Matsushita, Yoon Seok Roh, Amirali Kiyani, Ekihiro SekiDepartment of Medicine, Division of Gastroenterology, Cedars-Sinai Medical center, Los Angeles CA, USA
4_19ACUTE ALCOHOLIC HEPATITIS AND ALCOHOLIC LIVER DISEASE WITH BRIEF ABSTINENCE: APPROPRIATE INDICATIONS FOR LIVER TRANSPLANTATION?Schneekloth, TDMayo Clinic, Rochester, MN, USA
4_20TLR7 contributes to develop alcoholic fatty liver diseaseMatsumoto H, Okazaki S, Sugimoto K, Yang S, Hirata Y, Kamakura YOsaka University, Japan
4_21AP-001 FOR TREATING PANCREATIC ADENOCARCINOMAEdderkaoui M, Chheda C, Soufi B, Murali R, Pandol SJCedars-Sinai Medical Center and University of California Los Angeles, USA
4_53Alcohol consumption confers a four-fold risk of homicide victimization in Swedish femalesHedlund J, Forsman J, Sturup J, Masterman TDEPARTMENT OF CLINICAL NEUROSCIENCE, KAROLINSKA INTITUTET AND DEPARTMENT OF FORENSIC PSYCHIATRY, NATIONAL BOARD OF FORENSIC MEDICINE, Sweden
NumberTitleAuthorsAffiliation
Preclinical CNS
1_41DISCRETE NEURONAL ENSEMBLES IN THE NUCLEUS ACCUMBENS CORE MEDIATE “INCUBATION” OF EtOH CRAVINGWeiss F, Laque A, Repunte-Canonigo V, De Ness G, Wagner GE, Kerr TM, Watry D, Hope BT, Sanna PP, Suto NThe Scripps Research Institute, Department of Molecular and Cellular Neuroscience, USA
1_42ADOLESCENT NICOTINE AND ALCOHOL EXPOSURE - EFFECTS ON ENDOGENOUS OPIOID PEPTIDES IN RAT BRAINGranholm L, Segerström L, Nylander IUppsala University, Sweden
1_43Voluntary ethanol consumption during adolescence Primes the brain reward system to be more responsive to nicotine during adulthoodG.A. Deehan Jr., A.L. Bracken, C.P. Knight, R.A. Waeiss, W.J. McBride, R.L. Bell, S. R. Hauser, Z.A. RoddIndiana University: School of Medicine, USA
1_44DETERMINING THE NEUROCHEMICAL BASIS OF ETHANOL REWARD AND ANXIOLYSIS IN THE CENTRAL AMYGDALAChristopher P. Knight, Gerald A. Deehan Jr., R. Aaron Waiess, Sheketha R. Hauser, William J McBride, Zachary A RoddIndiana University: School of Medicine, USA
1_45GABA INTERNEURONS WITHIN THE BASOLATERAL AMYGDALA ARE ACTIVATED BY PRESENTATION OF A EXCITATORY CONDITIONED CUES.R. Hauser, G.A. Deehan Jr., C.P. Knight, R.A. Waeiss, W.J. McBride, William A, Truitt, Z.A. RoddIndiana University: School of Medicine, USA
1_46OPERANT SELF-ADMINSTRATION OF RED BULL® AND ALCOHOL: A QUESTION OF ALCOHOL CONTENTLópez-Moreno JA, Roldán M, Echeverry-Alzate V, Giné E, Calleja-Conde J, Rodríguez de Fonseca F, Bühler KMComplutense University of Madrid, Spain
1_47LONGTIME EFFECTS OF ETHANOL AND ITS METABOLITE ACETALDEHYDE ON BK CHANNEL ACTIVITY IN GH3 CELLS.A. G. Handlechner, A. Hermann, R. Fuchs, T. M. WeigerUniversity of Salzburg, Department of Cell Biology and Physiology, Austria
1_48Metabolic Shift of the Kynurenine Pathway Impairs Drug Seeking and RelapseValentina Vengeliene, Nazzareno Cannella, Tatiane Takahashi, Martin Rossmanith, Rainer SpanagelCentral Institute for Mental Health, Germany
1_49Characterization and modulation of neuronal ensembles involved in reward learningMartin Roßmanith, Valentina Vengeliene, Anita Hansson, Rainer SpanagelCentral Institute for Mental Health, Germany
1_50VOLUNTARY PHYSICAL EXERCISE CAN BLOCK ETHANOL-INDUCED CONDITIONED PLACE PREFERENCE IN MICE: THE ROLE OF TRANSCRIPTIONAL FACTOR CREB AND DEACETYLASE ISOZYMES SIRT-1 AND SIRT-2 IN SPECIFIC BRAIN TISSUESContó, MB, D’ Almeida, V, Camarini, RUniversidade de São Paulo, Brazil
1_51IDENTIFICATION OF AN INHIBITORY ALCOHOL BINDING SITE IN GABAA RHO1J. R. Trudell; C. M. Borghese; C. I. Ruiz; U. S. Lee; M. A. Cullins; E. J. Bertaccini; R. A. HarrisStanford School of Medicine, Stanford, Ca 94305, USA
1_52GUT-BRAIN AXIS: INVOLVEMENT OF GASTROINTESTINAL HORMONES IN ALCOHOL USE DISORDERVallöf D, Engel JA, Jerlhag EInstitute of Neuroscience and Physiology, Department of Pharmacology, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
1_53GABAB receptor regulation of glutamate release, spatial learning, and alcohol drinking in the prefrontal cortex of adolescent and adult C57Bl/6J mice.Roberto I. Melendez and Lemuel M. MelecioUniversity of Puerto Rico, Puerto Rico
1_54GENDER DIFFERENCES IN THE INFLAMMATORY CYTOKINE AND CHEMOKINE PROFILES INDUCED BY BINGE ETHANOL DRINKING IN ADOLESCENCEMontesinos J, Pascual M, Marcos M, García-García F, Torres JL, Costa-Alba P, Laso FJ, Guerri CDepartment of Molecular and Cellular Pathology of Alcohol, Príncipe Felipe Research Center, Valencia, Spain
1_55SIAH1 MEDIATES ETHANOL-INDUCED APOPTOSIS IN NEURAL CREST CELLS BY CBP/P300-MEDIATED ACETYLATION OF P53Yuan FQ, Liu J, and Chen S-YUniversity of Louisville Health Sciences Center, USA
1_56P2X7 RECEPTOR ANTAGONISM INHIBITS INFLAMMATORY RESPONSE IN BRAIN INDUCED BY EXPOSURE TO COMBINED ETHANOL AND HIGH-FAT DIETAsatryan L, Freire D, Lazaro RG, Tsukamoto H and Davies DLUniversity of Southern California Los Angeles, USA
1_57ETHANOL-PRODUCED BIOCHEMICAL AND MORPHOLOGICAL CHANGES IN THE RAT BRAIN ARE ANTAGONIZED BY THYROTROPIN-RELEASING HORMONE AND ITS SYNTHETIC PENTAPEPTIDE ANALOGPronko PS, Satanovskaya VI, Khomich TI, Zimatkin SM, Kandyba NI, Golubovich VP, Martinovich VP, Polikarpova VIInstitute of Biochemistry of Biologically Active Compounds, NAS of Belarus, Grodno, Belarus; 2Grodno State Medical University, Grodno, Belarus
1_58DISTINCT ROLES FOR RASGRF1 AND RASGRF2 IN COCAINE-MEDIATED BEHAVIORSOlevska A, Brambilla R, Santos E, Spanagel R, Bernardi RECentral Institute of Mental Health, Mannheim, Germany
1_59Persistent strengthening of the prefrontal cortex - nucleus accumbens pathway during incubation of cocaine-seeking behaviorCatarina Luís, Nazzareno Cannella, Rainer Spanagel, Georg Köhr Central Institute for Mental Health, Germany
1_60P2X4 RECEPTORS WITHIN THE BRAIN DOPAMINE REWARD SYSTEM PLAY AN IMPORTANT ROLE IN THE REGULATION OF ETHANOL-INTAKEDaryl L. DaviesUniversity of Southern California , USA
Clinical CNS – Treatment – Translation – Neuroimaging
2_41NEUROCOGNITION AND INHIBITORY CONTROL IN POLYSUBSTANCE USERS: COMPARISON WITH ALCOHOL-ONLY USERS AND CHANGES WITH ABSTINENCESchmidt TP, Pennington DL, Cardoos SL, Durazzo TC, Meyerhoff DJUniversity of California, San Francisco, USA
2_42CYTOKINE LEVEL CHANGES FOLLOWING ACUTE ETHANOL INTOXICATION IN HEALTHY MEN: A CROSS-OVER STUDYNeupane SP, Skulberg A, Skulberg KR, Salvatore S, Aass HC and Bramness JGNorwegian Centre for Addiction Research, Norway
2_43THE BEHAVIORAL EXPLORATION OF ATTENTIONAL ALTERATIONS IN BINGE DRINKINGLannoy S, Heeren A, Billieux J, Maurage PUniversité Catholique de Louvain, Louvain-la-Neuve, Belgium
2_44DO APPETITIVE GUT HORMONES ATTENUATE EATING AND ADDICTIVE BEHAVIOURS IN ALCOHOL AND NICOTINE DEPENDENCE: THE GUT HORMONES IN ADDICTION STUDY?Goldstone AP, Nestor LJ, Pannekoek JN, Ling YY, Akavarapu S, Kobson B, Munafo M, Lingford-Hughes AR, Nutt DJImperial College London, UK
2_45BINGE DRINKING AND FUNCTIONAL BRAIN CONNECTIVITY: A RESTING-STATE FMRI STUDYSousa S, Sampaio A, Marques P & Crego ANeuropsychophysiology Lab, CIPsi, School of Psychology, University of Minho, Portugal
2_46Neural Activity in Reward and Control Regions During Intertemporal Monetary Choices is Associated with Alcohol Use and Sexual RiskGardiner CK, Thayer RE, Sabbineni A, Karoly HC, Gillman AS, Claus EW, Hutchison KE, Bryan ADUniversity of Colorado Boulder, USA
2_47TRANSCUTANEOUS ELECTRICAL ACUPOINT STIMULATION COMBINED WITH DIAZEPAM: A BETTER CHOICE IN TREATMENT OF ACUTE ALCOHOL WITHDRAWAL SYMPTOMSChen X, Yang JP, Yuan W, Song YShandong Mental Health Center, China
2_48BACLOFEN IN THE TREATMENT OF ALCOHOL WITHDRAWAL: A SAFE ALTERNATIVE TO BENZODIAZEPINES ? PRELIMINARY RESULTS.Jegham S, Crunelle CL, Vanderbruggen N, Matthys FVrije Universiteit Brussel (VUB), Belgium
2_49Verbal memory difficulties associated to binge drinking trajectory in college students: 6 years follow-upCarbia, C; Cadaveira, F; Caamaño-Isorna, F; Piñeiro, M; Corral, MUniversidade de Santiago de Compostela, Spain
2_50Hazardous alcohol consumption after methadone initiation in patients switching from Buprenorphine treatment vs. Methadone incident users: implications for clinical management.Marie Costa, Sandra Nordmann, Antoine Vilotitch, Laurent Michel, Marion Moral, Bruno Spire, Gwenaelle Maradan, Alain Morel, Perrine Roux, Marc Tanti, M.Patrizia Carrieri, and the ANRS Methaville study group3. INSERM, UMR_S 912, « Sciences Economiques & Sociales de la Santé et Traitement de l'Information Médicale » (SESSTIM), France
2_51SIGNIFICANT REDUCTIONS IN ALCOHOL USE AFTER HEPATITIS C TREATMENT: RESULTS FROM THE FRENCH ANRS CO13-HEPAVIH COHORTRod Knight, Perrine Roux, Antoine Vilotitch, Fabienne Marcellin, Eric Rosenthal, Laure Esterle, Stéphanie Dominguez, Philippe Sogni, Dominique Salmon-Ceron, Bruno Spire, Patrizia Carrieri for the ANRS-CO13-HEPAVIH Study Group3. INSERM, UMR_S 912, « Sciences Economiques & Sociales de la Santé et Traitement de l'Information Médicale » (SESSTIM), France
2_52VERY INTEGRATED PROGRAM (VIP): HEALTH PROMOTION FOR ALCOHOL AND DRUG ADDICTED PATIENTS, A RANDOMIZED CONTROLLED TRIALHovhannisyan K, Skagert E, Tønnesen H, Adami JLund University, Sweden
2_53AREA OF CORPUS CALLOSUM AND HOMOCYSTEINE LEVELS IN ALCOHOLIC PATIENTSRomero-Acevedo L, Quintero-Platt G, Monereo-Muñoz M, González-Arnay E, Martín-González C, Pérez-Hernández O, Muñiz-Montes JR, González-Reimers EServicio de Medicina Interna, Hospital Universitario de Canarias. Tenerife, Canary Islands, Spain.
2_54BRAIN ATROPHY AMONG ALCOHOLICSMartín-González C, Romero-Acevedo L, Quintero-Platt G, Fernández-Rodríguez C, Pérez-Hernández O, Santolaria-Fernández F, Hernández-Luis R, González-Reimers EServicio de Medicina Interna, Hospital Universitario de Canarias. Tenerife, Canary Islands, Spain.
2_55PHYSICIAN TRAINING AND MONITORING PLAN TO ENSURE FIDELITY OF A BRIEF INTERVENTION CLINICAL TRIALBurina EA, Balachova T, Bonner B, Chaffin M, Grandilevskaya IV, Isurina GL, Shapkaitz VA, Tsvetkova LA, Volkova ENSaint-Petersburg State University, Russia
2_57THE EXECUTIVE FUNCTION OF HEAVY ALCOHOL USERS: THE EFFECT OF ALCOHOL-RELATED CUESLi X, Zeng N, Li WDepartment of Psychology, Zhejiang Normal University, Jinhua, China
2_59THE IMPACT OF LAT TYPOLOGY CONTAINING PHARMACOTHERAPY GUIDELINES ON ALCOHOL ADDICTS’ COSTS OF MEDICAL CARERancic N, Jakovljevic M, Jovanovic M, Babic S, Djordjevic N, Vyssoki BCentre for Clinical Pharmacology Medical Faculty Military Medical Academy, University of Defence, Belgrade, Serbia
2_60THE EFFECTIVENESS OF STRESS MANAGEMENT TECHNICS ON ALCOHOLIC PATIENTSM. RamakrishnanSRM University, India
Genetics - Diagnosis - FASD
3_2The OPRM1 A118G polymorphism (rs1799971) and alcohol dependenceSamochowiec A , Samochowiec J , Grzywacz AUniniversity of Szczecin, Institute of Psychology, Department of Clinical Psychology, Poland
3_26ADDITIONAL DIAGNOSTIC MARKERS OF ALCOHOL ADDICTION BASED ON COMPLEX ESTIMATION OF ADDICTIVE STATUS (COMORBID ADDICTIONS).Vyglazova OV, Linskiy IVInstitute of Neurology, Psychiatry and Narcology of the AMS of Ukraine; Central Regional Hospital of Dergachy district, Kharkiv region, Ukraine
3_27PHOSPHATIDYLETHANOL IN ASSESSING ALCOHOL USE AMONG INJURED PATIENTS IN AN EMERGENCY DEPARTMENTKabashi S, Wilson T, Vindenes V, Bogstrand STNorwegian Institute of Public Health, Oslo, Norway
3_28Confirmation of Thyroxine Treatment for Fetal Alcohol Spectrum Disorders in a Vulnerable BreedTunc-Ozcan, E, Ferreira, AB, Redei, EENorthwestern University, USA
3_29ASSAYS OF GGT-CDT COMBINATION FROM MATERNAL SERUM IMPROVES THE DETECTION OF PRENATAL ALCOHOL EXPOSURENiemelä O, Niemelä S; Ritvanen A, Gissler M, Bloigu A, Vääräsmäki M, Kajantie E; Werler MM, Surcel HMMedical Research Unit, Seinäjoki Central Hospital and University of Tampere, Finland
3_30LIVER ENZYME ABNORMALITIES IN ALCOHOL CONSUMERS: WHERE DO THE SAFE LIMITS OF ALCOHOL CONSUMPTION STAND?Niemelä O, Niemelä MV, Bloigu R, Aalto M, Laatikainen TMedical Research Unit, Seinäjoki Central Hospital and University of Tampere, Finland
3_31RALDH2 VARIANTS WITH REDUCED ACTIVITY GENETICALLY PREDISPOSE THE EMBRYO TO FASDShabtai Y, Liu S, Hicks GG and Fainsod AFaculty of Medicine, the Hebrew University of Jerusalem; Israel
3_32ABERRANT RADIAL MIGRATION AND ITS LONG-TERM CONSEQUENCES IN A MOUSE MODEL OF FASDDelatour LC, Yeh HHThe Geisel School of Medicine at Dartmouth, Department of Physiology and Neurobiology, USA
3_33EFFECTIVENESS OF VARIOUS ALCOHOL SCREENING INSTRUMENTS FOR DETECTING ALCOHOL USE DISORDER IN THE JAPANESE PRIMARY CARE SETTINGHisashi Yoshimoto, Ayumi TakayashikiUniversity of Tsukuba, Japan
Epidemiology
4_22CONSEQUENCES OF BINGE DRINKING IN COLLEGE STUDENTS: 9 YEAR FOLLOW-UP OF THE COMPOSTELA COHORTMoure-Rodríguez L, Doallo S, Carbia C, Corral M, Rodriguez Holguin S, Cadaveira F, Caamaño- Isorna FPublic Health. Universidade de Santiago de Compostela. CIBERESP., Spain
4_23EXPLANATORY FACTORS OF THE TWO MAJOR PATTERNS OF ALCOHOL CONSUMPTION IN COLLEGE STUDENTS: 9 YEARS FOLLOW-UP OF THE COMPOSTELA COHORT.Moure-Rodríguez L, Doallo S, Carbia C, Corral M, Rodriguez Holguin S, Cadaveira F, Caamaño- Isorna FComplexo Hospitalario Universitario de Ourense, Spain
4_24ALCOHOL USE DURING UNDERGRADUATE YEARS: CHARACTERIZATION OF PROFILESGómez P, Moure Rodriguez L, Corral M, Carbia C, Cadaveira F, Caamano Isorna FUniversidade de Santiago de Compostela, Spain
4_25BINGE DRINKING ASSOCIATED WITH A HIGHER RISK TO ALCOHOL PROBLEMS AMONG BRAZILIAN COLLEGE STUDENTS: A WEB-BASED STUDYBedendo, A; Andrade, A L M; Souza-Formigoni, M L O; Noto, A RDepartamento de Psicobiologia - Universidade Federal de São Paulo (UNIFESP). São Paulo - Brazil
4_26SELF-RATING EFFECTS OF ALCOHOL (SRE) AND ITS CORRELATES IN KOREAN MEDICAL STUDENTSLee BR, Kim SK, Schuckit MA, Stadlin ASchool of Medicine, Chungbuk National University, South Korea
4_27CORRELATES OF BINGE DRINKING IN ALCOHOL DEPENDENT PATIENTS – A PILOT STUDY FROM A TERTIARY CENTRE IN SOUTH INDIASoundararajan S, Purushottam M, Murthy PMBBS, PhD scholar, Department of Clinical Neurosciences & Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences(NIMHANS), Bangalore, India
4_28CHANGES FOR FIRST-TIME DRINK DRIVING OFFENDERS IN GENEVA (SWITZERLAND) OVER A 10-YEAR PERIODJORIS LAMBERT S, FAVRAT B, MICHIELS W, VAUCHER P, GACHE PUnit of Traffic Medicine and Psychology, University Centre of Legal Medicine, Geneva University Hospitals, Switzerland
4_29ESTIMATION OF THE NEED FOR COMMUNITY REHABILITATION FACILITIES FOR THE REHABILITATION OF ALCOHOLICS IN JAPANMinobe R, Osaki Y, Higuchi SNational Hospital Organization Kurihama Medical and Addiction Center, Japan
4_30The persons suffering from alcohol use disorder represented low Sense of Coherence -A multi-center study in Japan-Cho T, Tanaka M, Kobayashi O, Iba A, Sakuma H,Hashimoto N, Tanaka D, Muto T, Fukuda T, Noda T, Tsujimura S, Hayasaka T, Itabashi T, Yumoto Y, Sunami T, Nakano H, Bessho K, Nakamuta M, Mizuno K, Shinjo K, Takahashi N, Kuno K, Egami T, Hamamoto T, Morikawa MMental Care Center, Prefecture of Mie, Japan
4_31ALCOHOL USE AND OTHER CORRELATES OF ELECTRONIC-JOINT USE AND KNOWLEDGEFrohe T; Leeman RF; Sartor C; Ecker A; Kraus S; Foster DWUniversity of Florida, USA
4_32HIV RISK PATTERNS AMONG RUSSIAN WOMEN AT-RISK FOR ALCOHOL-EXPOSED PREGNANCIESBalachova T, Shaboltas A, Bohora S, Bonner B, Burina E, Chaffin M, Isurina G, Nasledov A, Skitnevskaya L, Tsvetkova L, Volkova EThe University of Oklahoma Health Sciences Center, USA
4_33A META-ANALYSIS OF ACUTE ALCOHOL USE AND THE RISK OF SUICIDE ATTEMPTBorges G, Bagge C, Cherpitel CJ, Conner K, Orozco R, Rossow IInstituto Nacional de Psiquiatria (Mexico City), Mexico
4_34HEAVY DRINKING TRAJECTORIES AMONG THAI ALCOHOL-DEPENDENT PATIENTS: A 1-YEAR FOLLOW-UPSrikosai S, Thitidilockrat, Booncharoen H, Chainoy D, Wittayanookulluk A, Rungsiwaroj N, Srithammachart L, Wonghongkul T
Chiang Mai University, Thailand
4_35PROFILING OF ALCOHOL ADDICTED PERSONS IN CRETE: 10 YEARS OF EXPERIENCE OF THE ALCOHOL OUTPATIENT CLINIC OF HERAKLION.Grinakis E, Koulentaki M, Sfakianaki K, Liodaki N, Mouzas JALCOHOL OUTPATIENT CLINIC, UNIVERSITY HOSPITAL OF CRETE, Greece
4_36Differences in psychiatric symptoms and personalities are larger between early and late onset of excessive drinking than between gendersSchückher F, Björk T, Berglund K, Berggren U, Balldin J, Engström I, Fahlke CUniversity Health Care Research Center, Faculty of Medicine and Health, Örebro University, SE 701 82 Örebro, Sweden
4_37HEAVY AND EXTREME BINGE DRINKING IN A CLINICAL SAMPLE OF ADOLESCENTS WITH ALCOHOL PROBLEMSMartin C, Creswell K, Jackson K, Skrzynski C, Bachrach R, Chung T, Clark DUniversity of Pittsburgh Department of Psychiatry, USA
4_38Hospitalization for Alcohol Dependence, a Review of 100 AdmissionsMcDonough, M; Sung-Lin Yang, SFootscray Hospital, Melbourne, Australia
4_39ASSOCIATIONS BETWEEN ALCOHOL ABUSE AND HEALTH CONSCIOUSNESS IN JAPAN: RESULTS FROM AN INTERNET SURVEYItoh H, Matsushita S, Imanari T, Takeshima T, Higuchi SNational Hospital Organization, Kurihama Medical and Addiction Center, Japan
4_40TRENDS AND PROJECTIONS OF REGULAR DRINKING: ANALYSIS OF THE THAI NATIONAL HEALTHPolathep Vichitkunakorn, Surichai Bilheem, Sawitri AssanangkornchaiEpidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand
4_41The suicide-related problems and their life histories among the alcohol-dependent inpatients with psychiatric comorbidities in JapanTanaka M, Tomohiro Shirasaka T, Cho T, Fukuda T, Kubo-Tamayose N, Noda T, Nakano WKoryo Hospital, yamaguchi, Japan
4_42THE INCIDENCE OF DRINKING AMONG YOUNG PEOPLE AND ITS BEHAVIORAL EFFECTs – FINDINGS FROM A NATIONWIDE SURVEY IN JAPANYumoto Y, OSAKI Y, Matsushita S, Higuchi SNational Hospital Organization Kurihama Medical and Addiction Center, Japan
4_43ALCOHOL PROBLEMS IN INDONESIA: A DEVELOPING COUNTRYSiste KUniversity of Indoenesia, Indonesia
4_44Well-being, Mental Health Problems, and Alcohol Experiences among Young Swedish Adolescents: a General Population StudyBoson K, Berglund K, Wennberg P and Fahlke CDepartment of Psychology, University of Gothenburg, Sweden
4_45CO-OCCURRING DEPRESSION AND ALCOHOL MISUSE IS UNDER-IDENTIFIED IN GENERAL PRACTICE: A CROSS-SECTIONAL STUDYHobden B, Bryant J, Sanson-Fisher R, Oldmeadow C, Carey MUniversity of Newcastle, Australia
4_46ARE ALCOHOL USE DISORDERS ASSOCIATED WITH Internet USE DISORDER? – DATA FROM THE GENERAL ADULT POPULATION AND CLINICAL SAMPLES IN JAPANMihara S, Nakayama H, Maezono M, Koshino H, Kitayuguchi T, Hashimoto T, Osaki Y, Higuchi SNational Hospital Organization Kurihama Medical and Addiction Center, Japan
4_47DIFFERENCES ON ALCOHOL EXPECTATIONS AND CONSUMPTION IN TEENAGERS FROM A MULTICULTURAL POPULATION.Díaz Geada A, Busto Miramontes A, Caamano Isorna F1. Public Health. Universidade de Santiago de Compostela. CIBER-ESP. Spain. 2. Preventive Medicine. University Hospital of Ourense. Spain
4_48Changes in alcohol and cannabis use among Thai population over 10 years : Is there an association?Kanittha Thaikla, Sawitri AssanangkornchaiResearch Institute for Health Sciences, Chiang Mai University, Thailand
4_49Alcohol drinking patterns and cardiovascular disease - is there a socioeconomic gradient for benefit or harm?Degerud EM, Ystrøm E, Ariansen I, Graff-Iversen S, Tambs K, Knudsen GP, Normann PT, Høiseth G, Davey-Smith G, Zuccolo L, Tell GS, Mørland J, Næss ØNorwegian Institute of Public Health, Oslo, Norway
4_50FACTORS AFFECTING THE DECISION TO USE CONDOMS AMONG AT-RISK WOMEN IN RUSSIADiakonova-Curtis D, Balachova T, Shaboltas A, Bonner B, Chaffin M, Batluk JSt. Petersburg State University, St. Petersburg, Russia
4_51Self-reports about physical abuse victimization among women who drink at risk in the Nizhny Novgorod Region in RussiaSkitnevskaya L.V., Volkova I.V., Volkova E.N., Balachova T.N.Nizhny Novgorod State Pedagogical University n.a.K.Minin, Nizhny Novgorod, Russia
4_52Estimation of the number of alcohol-related death in JapanMatsumoto H, Nakama K, Yoshizawa H, Ishida T, Sugimoto K, Katada ROsaka University, Japan
4_54POST COURSE EXPERIENCE ON DRUG SCREENING AND INTERVENTION PERFORMED BY HEALTH PROFESSIONALS AND SOCIAL WORKERSCarneiro APL, Souza-Formigoni MLOUniversidade Federal de Sao Paulo, Brazil
4_55STUDENTS WORRY ABOUT THE IMPACT OF ALCOHOL ON QUALITY OF LIFE: ROLES OF FREQUENCY OF BINGE DRINKING AND DRINKER SELF-CONCEPT.Luquiens Amandine, Falissard Bruno, Aubin Henri-JeanDépartement de psychiatrie et d’addictologie, Hôpital Paul Brousse, University of Paris-Saclay, University of Paris-Sud, UVSQ, CESP, INSERM U 1178, APHP Villejuif, France
4_56PREVALENCES OF BINGE DRINKING AND ALCOHOL RISKY CONSUMPTION IN COLLEGE STUDENTS: 9 Years Follow-up of the Compostela Cohort.L Moure-Rodríguez, D Bromberg, S Doallo, E Lopez-Caneda, M Corral M, S Rodríguez Holguín, F Cadaveira, F Caamaño- Isorna.Public Health. Universidade de Santiago de Compostela. CIBERESP., Spain