Good Research Practice in preclinical research: Publish robust data or perish

Sandra Helinski

Anton Bespalov
Partnership for Assessment and Accreditation of Scientific Practice
Heidelberg, Germany

There is no doubt that publishing is important and not publishing means putting scientific career in danger and slowing down the scientific process. A much more critical question is what should be published and when. First, there is a clear bias today towards publishing positive data and keeping negative data mostly in the drawers. However, it is the negative data that are essential for the self-correcting nature of science and for the scientific progress. Second, selective publishing and limited efforts to repeat study results before attempting to publish is another major issue. These unfortunately rather common practices start to take their toll on several areas of biomedical sciences. It will be discussed how these problems affect in vivo research in general and alcohol research in particular.